Author

D. Ricci

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Bioengineering· 1 Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

A. Espinosa-Ruiz· 1 shared A. Fernandez-del-Carmen· 1 shared A. Granell· 1 shared A. Ladd· 1 shared A. Lodi· 1 shared A. M. Lillo· 1 shared A. Sinigaglia· 1 shared A. T. Zemla· 1 shared

Activity by Year

2020-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 10 mutual co-author links

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Curved chords = mutual co-authorship

1 shared paperBioengineering

A. Espinosa-Ruiz

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Computationally restoring the potency of a clinical antibody against SARS-CoV-2 Omicron subvariants

T. A. Desautels, K. T. Arrildt, A. T. Zemla, E. Y. Lau, F. Zhu, D. Ricci, S. Cronin, S. Zost, E. Binshtein, S. M. Scheaffer, B. Dadonaite, B. K. Petersen, T. B. Engdahl, E. Chen, L. S. Handal, , Carnahan

This paper computationally redesigns an antibody to restore potency against SARS-CoV-2 Omicron subvariants while maintaining efficacy against Delta and other variants.

Nature · May 8, 2024Peer-reviewedMicrobiology

Dually biofortified cisgenic tomatoes with increased flavonoids and branched-chain amino acids content

M. Vazquez-Vilar, A. Fernandez-del-Carmen, V. Garcia-Carpintero, M. Drapal, S. Presa, D. Ricci, G. Diretto, J. L. Rambla, R. Fernandez-Munoz, A. Espinosa-Ruiz, P. D. Fraser, C. Martin, A. Granell, D. Orzaez

This paper describes the development of cisgenic tomatoes enriched in flavonoids and branched-chain amino acids (BCAAs) through genetic engineering, showing significant increases in both metabolites and potential health benefits.

bioRxiv · Oct 31, 2022Bioengineering

Differential plasmacytoid dendritic cell phenotype and type I Interferon response in asymptomatic and severe COVID-19 infection

M. Severa, R. A. Diotti, M. P. Etna, F. Rizzo, S. Fiore, D. Ricci, M. Iannetta, A. Sinigaglia, A. Lodi, N. Mancini, E. Criscuolo, M. Clementi, M. Andreoni, S. Balducci, L. Barzon, , E. Coccia

This study compares plasmacytoid dendritic cell (pDC) phenotype and type I IFN response in asymptomatic and severe COVID-19 patients, finding differences in pDC frequency, phenotype, and cytokine levels.

bioRxiv · Apr 17, 2021Immunology

The interdomain helix between the kinase and RNase domains of IRE1α transmits the conformational change that underlies ER stress-induced activation.

D. Ricci, S. Tutton, I. Marrocco, M. Ying, D. Blumenthal, D. Eletto, J. Vargas, S. Boyle, H. Fazelinia, J. C. Paton, A. W. Paton, C.-H. A. Tang, C.-C. A. Hu, T. Gidalevitz, Y. Argon

This study identifies the interdomain helix between IRE1α kinase and RNase domains as critical for transmitting conformational changes during ER stress, revealing its role in regulating oligomerization, RNase activity, and kinase function.

bioRxiv · Jan 14, 2020 · PreprintBiochemistry