Author

F. Chen

University of Southern California

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 21 Cell Biology· 21 Immunology· 13 Microbiology· 13 Plant Biology· 6 Animal Behavior & Cognition· 4

Signature Assays, Organisms & Methods

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Approach:experimental assay· 69 Organism:human· 43 Research Focus:cell type annotation· 31 Research Focus:host-pathogen & immune response· 29 Approach:statistical model· 29 Organism:mouse· 27 Assay:bulk RNA-seq· 23 Research Focus:differential expression· 20

Frequent Co-Authors

Y. Wang· 15 shared Y. Zhang· 14 shared Z. Zhang· 10 shared X. Wang· 9 shared S. Li· 8 shared D. Chen· 7 shared H. Wang· 7 shared J. Zhu· 7 shared

Activity by Year

2017-2025 · peak 26/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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Curved chords = mutual co-authorship

15 shared papersCancer Biology

Y. Wang

Mutual co-authors in cluster

Author profile →

99 papers

Recent·Most cited

Diverse, abundant and novel viruses infecting \"unculturable\" but abundant marine bacteria

Z. Zhang, F. Chen, X. Chu, H. Zhang, H. Luo, F. Qin, Z. Zhai, M. Yang, J. Sun, Y. Zhao

The paper isolates and characterizes seven phages infecting Roseobacter RCA lineage bacteria, revealing genomic diversity and abundance in marine virosphere.

bioRxiv · Jul 11, 2019 · PreprintMicrobiology

Single cell RNA-seq reveals cellular diversity and developmental characteristics of human infant retina

J. Zhong, D. Chen, F. Hu, F. Chen, Z. Xu, J. Fang, J. Xu, S. Wang, L. Liang, C. Chai, X. Ding, J. Zhu, P. Ding, J. Xia, S. Jiang, , X. Sun

This study uses single-cell RNA-seq to analyze human infant retina, identifying cell types, communication networks, and developmental changes, providing a resource for retinal research and regenerative medicine.

bioRxiv · Apr 25, 2019 · PreprintCell Biology

Single cell RNA sequencing reveals cellular diversity of trisomy 21 retina

J. Wu, X. Ding, F. Hu, Z. Xu, S. Zhang, L. Liang, C. Chai, J. Zhong, S. Wang, X. Lin, Y. Chen, Q. Feng, J. Zhu, S. Jiang, J. Xia, , F. Chen

This study uses single-cell RNA sequencing to analyze the cellular diversity and molecular markers in the retina of a trisomy 21 fetus, revealing communication networks and novel markers.

bioRxiv · Apr 21, 2019 · PreprintCell Biology

Targeted mRNA demethylation using an engineered dCas13b-ALKBH5 fusion protein

J. Li, Z. Chen, F. Chen, Y. Ling, Y. Peng, N. Luo, H. Wang

This paper develops a CRISPR-Cas13b-based tool to specifically demethylate m6A modifications on target mRNAs, enhancing their stability and demonstrating efficient gene regulation with minimal off-target effects.

bioRxiv · Apr 20, 2019Cell Biology

MicroRNA-138 negatively regulates the hypoxia-inducible factor 1α to suppress melanoma growth and metastasis

h. qiu, F. Chen, M. Chen

This study identifies miRNA-138 as a negative regulator of HIF1α, showing its ability to suppress melanoma growth and metastasis through direct targeting of HIF1.

bioRxiv · Mar 3, 2019Cancer Biology

FabriEVEs: A dedicated platform for endogenous viral elements in fishes, amphibians, birds, reptiles and invertebrates

J. Zhong, J. Zhu, Z. Xu, G. Zou, J. Zhao, S. Jiang, W. Zhang, J. Xia, L. Yang, F. Li, Y. Gao, F. Chen, Y. Wu, D. Chen

FabriEVEs is a database that collects, classifies, and annotates endogenous viral elements in non-mammalian species, enabling comparative analysis and host-virus co-evolution studies.

bioRxiv · Jan 24, 2019 · PreprintEvolutionary Biology

Nanoscale fracture of defective popgraphene monolayer

F. Meng, M. Ni, F. Chen, J. Song, D. Wei

This study investigates the fracture behavior of defective popgraphene using molecular dynamics and continuum modeling, revealing how different defect types affect fracture stress.

bioRxiv · Nov 6, 2018Biophysics

Influence of elevated CO2 on development and food utilization of target armyworm Mythimna separata fed on transgenic Bt maize infected by nitrogen-fixing bacteria

Z. Li, Y. Song, L. Li, L. Wang, B. Liu, M. N. Parajulee, F. Chen

This study examines how elevated CO2 affects the development and food utilization of Mythimna separata larvae feeding on Bt maize infected with nitrogen-fixing bacteria.

bioRxiv · Mar 31, 2018Ecology

The Kobresia pygmaea ecosystem of the Tibetan highlands – origin, functioning and degradation of the world’s largest pastoral alpine ecosystem

G. Miehe, P.-M. Schleuss, E. Seeber, W. Babel, T. Biermann, M. Braendle, F. Chen, H. Coners, T. Foken, T. Gerken, H.-F. Graf, G. Guggenberger, S. Hafner, M. Holzapfel, J. Ingrisch, , K. Wesche

This paper reviews the origin, functioning, and degradation of the Kobresia pygmaea ecosystem in the Tibetan highlands, identifying key factors affecting its resilience and carbon dynamics.

bioRxiv · May 11, 2017Ecology