Author

F. Ellett

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 4 Immunology· 3

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 6 Approach:experimental assay· 6 Research Focus:host-pathogen & immune response· 4 Organism:human· 4 Research Focus:cell type annotation· 3 Organism:zebrafish· 3 Assay:imaging· 2 Assay:proteomics· 2

Frequent Co-Authors

D. Irimia· 4 shared A. Hadjitheodorou· 2 shared C. A. Loynes· 2 shared C. C. Reyes-Aldasoro· 2 shared G. R. R. Bell· 2 shared J. A. Theriot· 2 shared S. R. Collins· 2 shared A. Andrianopoulos· 1 shared

Activity by Year

2017-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 15 mutual co-author links

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4 shared papersCell Biology

D. Irimia

Mutual co-authors in cluster

Author profile →

7 papers

Recent·Most cited

Pulses of Class I PI3kinase activity identify the release and recapture of prey from neutrophil phagosomes

C. F. Muir, C. C. Reyes-Aldasoro, F. Ellett, T. Prajsnar, Y. X. Ho, A. Bernut, C. A. Loynes, S. Elworthy, K. A. Bowden, A. J. Cadby, L. Prince, J. S. King, A. M. Condliffe, S. Renshaw

The paper identifies pulsatile Class I PI3K activity on neutrophil phagosomes during bacterial infection, suggesting phagosomes reopen and reclose to release or restart digestion.

bioRxiv · Feb 29, 2024 · PreprintCell Biology

Mechanical competition promotes selective listening to receptor inputs to resolve directional dilemmas in neutrophil migration

A. Hadjitheodorou, G. R. R. Bell, F. Ellett, D. Irimia, R. Tibshirani, S. R. Collins, J. A. Theriot

This study shows neutrophils resolve directional dilemmas by committing to one leading edge late in the decision process, influenced by mechanical stretching and receptor inputs.

bioRxiv · Feb 21, 2022Cell Biology

Neutrophil Profiles of Pediatric COVID-19 and Multisystem Inflammatory Syndrome in Children

B. P. Boribong, T. J. LaSalle, Y. C. Bartsch, F. Ellett, M. E. Loiselle, J. P. Davis, A. L. K. Gonye, S. Hajizadeh, J. Kreuzer, S. Pillai, W. Haas, A. G. Edlow, A. Fasano, G. Alter, D. Irimia, , L. M. Yonker

The paper identifies neutrophil activation and NET formation in MIS-C linked to SARS-CoV-2 immune complexes, differing from acute pediatric COVID-19.

bioRxiv · Dec 18, 2021Immunology

Directional reorientation of migrating neutrophils is limited by suppression of receptor input signaling at the cell rear through myosin II activity

A. Hadjitheodorou, G. R. R. Bell, F. Ellett, S. Shastry, D. Irimia, S. R. Collins, J. A. Theriot

bioRxiv · Apr 4, 2021Cell Biology

Megakaryocytes Display Innate Immune Cell Functions and Respond during Sepsis

D. Irimia, G. H. Frydman, F. Ellett, J. Jorgensen, A. L. Marand, L. Zukerberg, M. Selig, S. Tessier, K. H. K. Wong, D. Olaleye, C. R. Vanderburg, J. G. Fox, R. G. Tompkins

This study shows megakaryocytes have innate immune functions and respond during sepsis by chemotaxis, phagocytosis, and chromatin web release.

bioRxiv · Aug 21, 2019 · PreprintImmunology

β-glucan dependent shuttling of conidia from neutrophils to macrophages occurs during fungal infection establishment

V. Pazhakh, F. Ellett, J. O'Donnell, L. Pase, K. E. Schulze, R. S. Greulich, C. C. Reyes-Aldasoro, B. A. Croker, A. Andrianopoulos, G. J. Lieschke

The paper describes β-glucan-dependent conidial shuttling between neutrophils and macrophages during fungal infection, enhancing conidial survival and infection establishment.

bioRxiv · Jan 4, 2019Cell Biology

PGE2 production at sites of tissue injury promotes an anti-inflammatory neutrophil phenotype and determines the outcome of inflammation resolution in vivo

C. A. Loynes, J. A. Lee, A. L. Robertson, M. J. G. Steel, F. Ellett, Y. Feng, B. D. Levy, M. K. Whyte, S. A. Renshaw

This study shows that PGE2 promotes neutrophil reverse migration and anti-inflammatory signaling, aiding inflammation resolution in a zebrafish model.

bioRxiv · Dec 20, 2017Immunology