Author

J. P. Davis

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Cell Biology· 1 Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:cell type annotation· 2 Organism:human· 2 Assay:proteomics· 2 Organism:bacteria (other)· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:drug response / drug discovery· 1 Assay:flow cytometry· 1

Frequent Co-Authors

S. Lindert· 2 shared A. Bui· 1 shared A. Fasano· 1 shared A. G. Edlow· 1 shared A. Gomez· 1 shared A. Ho· 1 shared A. I. Derman· 1 shared A. L. K. Gonye· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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2 shared papersBiochemistry

S. Lindert

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Targeting Troponin C with Small Molecules Containing Diphenyl Moieties: Calcium Sensitivity Effects on Striated Muscle and Structure Activity Relationship

E. R. Hantz, S. B. Tikunova, N. Belevych, J. P. Davis, P. J. Reiser, S. Lindert

The paper investigates small molecules targeting troponin C to enhance calcium sensitivity in cardiac and skeletal muscle without altering systolic calcium levels, identifying a potent sensitizer with an apparent affinity of 117 ± 17 M.

bioRxiv · Feb 6, 2023Biochemistry

Neutrophil Profiles of Pediatric COVID-19 and Multisystem Inflammatory Syndrome in Children

B. P. Boribong, T. J. LaSalle, Y. C. Bartsch, F. Ellett, M. E. Loiselle, J. P. Davis, A. L. K. Gonye, S. Hajizadeh, J. Kreuzer, S. Pillai, W. Haas, A. G. Edlow, A. Fasano, G. Alter, D. Irimia, , L. M. Yonker

The paper identifies neutrophil activation and NET formation in MIS-C linked to SARS-CoV-2 immune complexes, differing from acute pediatric COVID-19.

bioRxiv · Dec 18, 2021Immunology

The non-canonical interaction between calmodulin and calcineurin contributes to the differential regulation of plant-derived calmodulins on calcineurin.

B. Sun, X. Fang, C. N. Johnson, G. Hauck, J. P. Davis, P. M. Kekenes-Huskey

This study investigates how plant-derived calmodulin variants differentially regulate calcineurin through non-canonical interactions beyond calcium binding and canonical CaMBR binding.

bioRxiv · Jun 18, 2021Biochemistry

Isolation and characterization of Streptomyces bacteriophages and Streptomyces strains encoding biosynthetic arsenals

E. T. Montano, J. F. Nideffer, L. Brumage, M. Erb, A. I. Derman, J. P. Davis, E. Estrada, S. Fu, D. Le, A. Vuppala, C. Tran, E. Luterstein, S. Lakkaraju, S. Panchagnula, C. Ren, , J. Pogliano

This study identifies novel Streptomyces strains and phages with potential for antibiotic discovery and genetic manipulation.

bioRxiv · Jun 22, 2020 · PreprintMicrobiology

Binding of Calcium and Magnesium to Cardiac Troponin C

K. Rayani, J. T. Seffernick, Y. A. Li, J. P. Davis, A. Spuches, F. V. Petegem, R. J. Solaro, S. Lindert, G. F. Tibbits

This study quantifies Ca2+/Mg2+ binding to cardiac troponin C site II, showing Mg2+ can occupy site II and reduce Ca2+ affinity at physiological concentrations.

bioRxiv · Jun 14, 2020 · PreprintCell Biology