Author

F.-J. Gamo

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:plant (other)· 2 Assay:bulk RNA-seq· 1 Approach:deep learning· 1 Assay:fluorescence / live-cell microscopy· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

D. A. Fidock· 2 shared T. Yeo· 2 shared A. C. Aguiar· 1 shared A. Churchyard· 1 shared A. Khomiak· 1 shared A.-C. Uhlemann· 1 shared B. C. Fernandez· 1 shared B. Campo· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersMicrobiology

D. A. Fidock

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Machine Learning-based Phenotypic Imaging to Characterise the Targetable Biology of Plasmodium falciparum Male Gametocytes for the Development of Transmission-Blocking Antimalarials

O. Tsebriy, A. Khomiak, C. Miguel-Blanco, P. C. Sparkes, M. Gioli, M. Santelli, E. Whitley, F.-J. Gamo, M. J. Delves

The paper uses machine learning to analyze fluorescence microscopy images of Plasmodium falciparum gametocytes, characterizing the cellular effects of transmission-blocking molecules.

bioRxiv · Apr 22, 2023 · PreprintMicrobiology

Generation of a mutator parasite to drive resistome discovery in Plasmodium falciparum

K. Kumpornsin, T. Kochakarn, T. Yeo, M. Luth, R. D. Pearson, J. Hoshizaki, K. Schindler, S. Mok, H. Park, A.-C. Uhlemann, S. M. Cubel, V. Franco, M. Gomez-Lorenzo, F.-J. Gamo, E. Winzeler, , M. C. Lee

This study creates a mutator parasite of Plasmodium falciparum to enhance drug resistance discovery by increasing mutation rates and identifying resistance mechanisms.

bioRxiv · Aug 23, 2022 · PreprintMicrobiology

Preclinical characterization and target validation of the antimalarial pantothenamide MMV693183

L. E. de Vries, P. A. Jansen, C. Barcelo, J. Munro, J. M. Verhoef, C. F. A. Pasaje, K. Rubiano, J. Striepen, J. M. Bolscher, R. Henderson, T. Huijs, K. M. Koolen, P. K. Tumwebaze, T. Yeo, A. C. Aguiar, , K. J. Dechering

This paper characterizes MMV693183, a novel antimalarial compound targeting acetyl-CoA synthetase, showing in vitro and in vivo efficacy against Plasmodium species and transmission blocking.

bioRxiv · May 12, 2021Microbiology