Combinatorial immunotherapies overcome MYC-driven immune evasion
J. V. Lee, F. Houseley, C. Yau, D. Van de Mark, R. Nakagawa, G. Hemmati, G. A. Hernandez, J. Winkler, Y. Zhang, S. Samson, C. Baas, L. J. Esserman, L. J. Van't Veer, H. S. Rugo, M. Matloubian, A. Goga
This study shows that MYC-driven immune evasion in TNBC can be reversed by combining immunotherapies, leading to tumor regression in mice.
bioRxiv · May 7, 2021Cancer Biology