Author

H. S. Rugo

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

A. Goga· 2 shared J. V. Lee· 2 shared J. Winkler· 2 shared A. Abbasi· 1 shared A. Detweiler· 1 shared A. Nanjaraj· 1 shared A. O. Pisco· 1 shared C. Baas· 1 shared

Activity by Year

2021-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersCancer Biology

A. Goga

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Author profile →

2 papers

Recent·Most cited

Dissecting the contributions of tumor heterogeneity on metastasis at single-cell resolution

J. Winkler, W. Tan, C. M. M. Diadhiou, C. S. McGinnis, A. Abbasi, S. Hasnain, S. Durney, E. Atamaniuc, D. Superville, L. Awni, J. V. Lee, J. H. Hinrichs, M. Y. Hein, M. Borja, A. Detweiler, , Z. Werb

This study analyzes single-cell transcriptomes of primary tumors and metastases from breast cancer models, identifying transcriptional differences and gene signatures linked to metastatic potential and patient outcomes.

bioRxiv · Aug 4, 2022 · PreprintCancer Biology

Combinatorial immunotherapies overcome MYC-driven immune evasion

J. V. Lee, F. Houseley, C. Yau, D. Van de Mark, R. Nakagawa, G. Hemmati, G. A. Hernandez, J. Winkler, Y. Zhang, S. Samson, C. Baas, L. J. Esserman, L. J. Van't Veer, H. S. Rugo, M. Matloubian, A. Goga

This study shows that MYC-driven immune evasion in TNBC can be reversed by combining immunotherapies, leading to tumor regression in mice.

bioRxiv · May 7, 2021Cancer Biology