Author

G. Berx

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:bulk RNA-seq· 2 Research Focus:cancer & tumor microenvironment· 2 Research Focus:drug response / drug discovery· 2 Organism:human· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

A. B. Dohlman· 1 shared A. G. Volk· 1 shared A. strikoudis· 1 shared A. Thiran· 1 shared B. Accordi· 1 shared B. Bornhauser· 1 shared B. T. Gutierrez Diaz· 1 shared B. Ueberheide· 1 shared

Activity by Year

2018-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperCancer Biology

A. B. Dohlman

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3 papers

Recent·Most cited

Colibactin-induced genotoxicity and colorectal cancer exacerbation critically depends on adhesin-mediated epithelial binding

M. Jans, M. Kolata, G. Blancke, M. Ciers, A. B. Dohlman, T. Kusakabe, M. Sze, A. Thiran, G. Berx, S. Tejpar, G. van Loo, I. D. Iliev, H. Remaut, L. Vereecke

This study shows that pks+ E. coli's ability to worsen colorectal cancer depends on adhesins that allow it to bind to host cells and produce the genotoxin colibactin.

bioRxiv · Aug 16, 2023 · PreprintCancer Biology

Establishment and characterization of a cell line and patient-derived xenograft (PDX) from peritoneal metastasis of low-grade serous ovarian carcinoma

E. De Thaye, K. Van de Vijver, J. Van der Meulen, J. Taminau, G. Wagemans, H. Denys, J. Van Dorpe, G. Berx, W. Ceelen, J. Van Bocxlaer, O. De Wever

The paper establishes and characterizes a PDX model and cell line from peritoneal metastasis of low-grade serous ovarian carcinoma, showing sensitivity to paclitaxel and trametinib.

bioRxiv · Sep 27, 2019Cancer Biology

USP7 cooperates with NOTCH1 to drive the oncogenic transcriptionalprogram in T cell leukemia

P. Ntziachristos, K. Arcipowski, Q. Jin, C. A. Martinez, Y. Zhu, B. T. Gutierrez Diaz, K. Wang, M. Johnson, A. G. Volk, F. Wang, J. wu, H. Wang, I. Sokirniy, P. Thomas, Y. A. Goo, , J. D Crispino

This study identifies USP7 as a key driver of T-cell leukemia by stabilizing NOTCH1 and JMJD3, showing USP7 inhibition blocks leukemia growth and suggests it as a therapeutic target.

bioRxiv · Jan 16, 2018Cancer Biology