Author

T. Kusakabe

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Cancer Biology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:host-pathogen & immune response· 3 Organism:mouse· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Organism:non-human primate· 1 Assay:proteomics· 1

Frequent Co-Authors

J. M. Lee· 3 shared K. Oyama· 2 shared M. Nishida· 2 shared Y. Kato· 2 shared A. B. Dohlman· 1 shared A. Masuda· 1 shared A. Nishimura· 1 shared A. Satsuka· 1 shared

Activity by Year

2021-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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3 shared papersBiochemistry

J. M. Lee

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Characterization of high affinity IgM and IgG monoclonal antibodies against norovirus variants GII.4 and GII.17

J. Tagawa, S. Yanaka, Y. Kato, A. Masuda, J. M. Lee, A. Senoo, K. Oyama, M. Nishida, T. Kusakabe, J. M. M. Caaveiro

This study generates and characterizes monoclonal IgM and IgG antibodies against norovirus variants GII.4 and GII.17, revealing differences in binding mechanisms and affinity.

bioRxiv · May 11, 2024Biochemistry

Colibactin-induced genotoxicity and colorectal cancer exacerbation critically depends on adhesin-mediated epithelial binding

M. Jans, M. Kolata, G. Blancke, M. Ciers, A. B. Dohlman, T. Kusakabe, M. Sze, A. Thiran, G. Berx, S. Tejpar, G. van Loo, I. D. Iliev, H. Remaut, L. Vereecke

This study shows that pks+ E. coli's ability to worsen colorectal cancer depends on adhesins that allow it to bind to host cells and produce the genotoxin colibactin.

bioRxiv · Aug 16, 2023 · PreprintCancer Biology

Highly efficient protein expression of Plasmodium vivax surface antigen, Pvs25 by silkworm, Bombyx mori, and its biochemical analysis.

T. Miyata, K. Minamihata, K. Kurihara, Y. Kamizuru, M. Gotanda, M. Obayashi, T. Kitagawa, K. Sato, M. Kimura, K. Oyama, Y. Ikeda, Y. Tamaki, J. M. Lee, K. Sakao, D. Hamanaka, , H. H. Ibrahim

This study expresses and purifies recombinant Pvs25 from silkworms, demonstrating its potential as a malaria transmission-blocking vaccine candidate with high immunogenicity.

bioRxiv · Mar 3, 2022 · PreprintBiochemistry

Clomipramine suppresses ACE2-mediated SARS-CoV-2 entry

Y. Kato, S. Yamada, K. Nishiyama, A. Satsuka, S. Re, D. Tomokiyo, J. M. Lee, T. Tanaka, A. Nishimura, K. Yonemitsu, H. Asakura, Y. Ibuki, Y. Imai, N. Kamiya, K. Mizuguchi, , M. Nishida

This study shows clomipramine inhibits SARS-CoV-2 entry into cardiomyocytes and synergizes with remdesivir to suppress infection.

bioRxiv · Mar 13, 2021 · PreprintPharmacology & Toxicology