Author

G. Leclercq

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:cell type annotation· 4 Research Focus:differential expression· 3 Approach:experimental assay· 3 Organism:human· 3 Assay:scRNA-seq· 3 Assay:bulk RNA-seq· 1 Assay:ChIP-seq· 1 Research Focus:clustering· 1

Frequent Co-Authors

T. Taghon· 4 shared B. Vandekerckhove· 3 shared F. Van Nieuwerburgh· 2 shared J. Roels· 2 shared M. Lavaert· 2 shared N. Vandamme· 2 shared P. Van Vlierberghe· 2 shared S. De Munter· 2 shared

Activity by Year

2020-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

4 shared papersImmunology

T. Taghon

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Type 1 immunity enables neonatal thymic ILC1 production

P. Tougaard, M. R. Perez, W. Steels, J. Huysentruyt, B. Verstraeten, J. Vetters, T. Divert, A. Goncalves, R. Roelandt, N. Takahashi, S. Janssens, T. B. Buus, T. Taghon, G. Leclercq, P. Vandenabeele

The paper shows type 1 immunity drives thymic production and peripheral migration of ILC1s in neonates.

Science Advances · Jan 19, 2024Peer-reviewedImmunology

Single-cell profiling identifies a spectrum of human unconventional intraepithelial T lineage cells

L. Billiet, L. De Cock, G. Sanchez Sanchez, R. L. Mayer, G. Goetgeluk, S. De Munter, M. Pille, J. Ingels, H. Jansen, K. Weening, E. Pascal, K. Raes, S. Bonte, T. Kerre, N. Vandamme, , B. Vandekerckhove

The paper identifies a spectrum of human unconventional intraepithelial T lineage cells using single-cell RNA sequencing and defines their phenotypic and transcriptomic features.

bioRxiv · May 24, 2022Immunology

The transcription factor RUNX2 drives the generation of human NK cells and promotes tissue residency

S. Wahlen, F. Matthijssens, W. Van Loocke, S. Taveirne, L. Kiekens, E. Persyn, E. van Ammel, Z. De Vos, S. De Munter, P. Matthys, F. Van Nieuwerburgh, T. Taghon, B. Vandekerckhove, P. Van Vlierberghe, G. Leclercq

This study shows that RUNX2 promotes human NK cell generation and tissue residency through IL-2Rβ induction, with implications for cancer therapy.

bioRxiv · May 2, 2022Immunology

Single cell profiling of immature human postnatal thymocytes resolves the complexity of intra-thymic lineage differentiation and thymus seeding precursors.

M. Lavaert, K. L. Liang, N. Vandamme, J.-E. Park, J. Roels, M. S. Kowalczyk, B. Li, O. Ashenberg, M. Tabaka, D. Dionne, T. L. Tickle, M. Slyper, O. Rozenblatt-Rosen, B. Vandekerckhove, G. Leclercq, , T. Taghon

The paper uses single-cell RNA sequencing to analyze immature human thymocytes and identifies thymus seeding precursors and T-lineage developmental pathways.

bioRxiv · Apr 7, 2020 · PreprintImmunology