T. Taghon

Type 1 immunity enables neonatal thymic ILC1 production

The paper shows type 1 immunity drives thymic production and peripheral migration of ILC1s in neonates.

Single-cell profiling identifies a spectrum of human unconventional intraepithelial T lineage cells

The paper identifies a spectrum of human unconventional intraepithelial T lineage cells using single-cell RNA sequencing and defines their phenotypic and transcriptomic features.

The transcription factor RUNX2 drives the generation of human NK cells and promotes tissue residency

This study shows that RUNX2 promotes human NK cell generation and tissue residency through IL-2Rβ induction, with implications for cancer therapy.

Single cell profiling of immature human postnatal thymocytes resolves the complexity of intra-thymic lineage differentiation and thymus seeding precursors.

The paper uses single-cell RNA sequencing to analyze immature human thymocytes and identifies thymus seeding precursors and T-lineage developmental pathways.

A cell atlas of human thymic development defines T cell repertoire formation

This study creates a cell atlas of the human thymus using scRNA-seq, revealing new cell populations and insights into T-cell development and TCR recombination.