Author

G. Subramanian

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Biophysics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:drug response / drug discovery· 2 Organism:bacteria (other)· 1 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Organism:plant (other)· 1

Frequent Co-Authors

R. Chandramohanadas· 2 shared Z. Bozdech· 2 shared A. Barty· 1 shared A. Katz· 1 shared A. Patra· 1 shared A. Xiong· 1 shared C. Kupitz· 1 shared C. T. Lim· 1 shared

Activity by Year

2018-2019 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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2 shared papersMicrobiology

R. Chandramohanadas

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Reticulocyte Infection Leads to Altered Behaviour, Drug Sensitivity and Host Cell Remodelling by Plasmodium falciparum.

R. Chandramohanadas, R. Naidu, T. T. Chu, J. Tripathi, Y. Hu, G. Subramanian, J. X. Tong, P. Tripathi, K. Fang, K. S. Tan, C. T. Lim, J. K. Chan, Z. Bozdech

This paper shows that Plasmodium falciparum infects reticulocytes with higher affinity, alters drug sensitivity, and remodels host cells through transcriptomic changes.

bioRxiv · Dec 2, 2019 · PreprintMicrobiology

Whole Cell Phenotypic Screening Of MMV Pathogen Box identifies Specific Inhibitors of Plasmodium falciparum merozoite maturation and egress.

A. Patra, T. Hingamire, M. Belekar, A. Xiong, G. Subramanian, Z. Bozdech, P. Preiser, D. Shanmugam, R. CHANDRAMOHANADAS

The paper screens the MMV Pathogen Box to identify inhibitors of Plasmodium falciparum merozoite maturation and egress, finding 12 potent and selective blockers.

bioRxiv · Sep 18, 2019 · PreprintMicrobiology

Enzyme Intermediates Captured "on-the-fly" by Mix-and-Inject Serial Crystallography

J. Olmos, S. Pandey, J. M. Martin-Garcia, G. Calvey, A. Katz, J. Knoska, C. Kupitz, M. S. Hunter, M. Liang, D. Oberthuer, O. Yefanov, M. Wiedorn, M. Heymann, M. Holl, K. Pande, , Our

This paper demonstrates a method to capture enzyme reactions in real-time using mix-and-inject serial crystallography, revealing antibiotic cleavage and kinetic transitions in Mycobacterium tuberculosis β-lactamase.

bioRxiv · Jan 18, 2018Biophysics