Author

H. B. Smith

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 5 Biochemistry· 1

Signature Assays, Organisms & Methods

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Research Focus:host-pathogen & immune response· 4 Organism:bacteria (other)· 3 Approach:experimental assay· 3 Assay:metabolomics· 2 Approach:biophysical modeling· 1 Research Focus:cell signaling & trafficking· 1 Approach:deep learning· 1 Approach:genetic perturbation / CRISPR· 1

Frequent Co-Authors

J.-D. Sauer· 3 shared D. Amador-Noguez· 2 shared D. M. Stevenson· 2 shared A. Anaya-Sanchez· 1 shared A. C. Varano· 1 shared A. J. Duncan· 1 shared C. C. Yoo· 1 shared C. M. Ajo-Franklin· 1 shared

Activity by Year

2017-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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3 shared papersMicrobiology

J.-D. Sauer

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Rules, hypergraphs, and probabilities: the three-level analysis of chemical reaction systems and other stochastic stoichiometric population processes

E. Smith, H. B. Smith, J. L. Andersen

The paper develops a three-level framework for analyzing stochastic chemical reaction systems, showing how constraints at earlier levels influence dynamics at later levels and applying it to biological sugar-phosphate chemistry.

bioRxiv · Dec 11, 2023Biochemistry

Listeria monocytogenes requires DHNA-dependent intracellular redox homeostasis facilitated by Ndh2 for survival and virulence

H. B. Smith, K. Lee, D. M. Stevenson, D. Amador-Noguez, J.-D. Sauer

This study shows that Listeria monocytogenes uses DHNA-dependent redox homeostasis via Ndh2 for survival and virulence, independent of respiration.

bioRxiv · Jan 13, 2023 · PreprintMicrobiology

Listeria monocytogenes requires cellular respiration for NAD+ regeneration and pathogenesis

R. Rivera-Lugo, D. Deng, A. Anaya-Sanchez, S. Tejedor-Sanz, V. M. Reyes Ruiz, H. B. Smith, D. V. Titov, J. D. Sauer, E. P. Skaar, C. M. Ajo-Franklin, D. A. Portnoy, S. H. Light

This study shows that Listeria monocytogenes uses cellular respiration for NAD+ regeneration, which is critical for its pathogenesis and survival in host cells.

bioRxiv · Nov 25, 2021Microbiology

Listeria monocytogenes GlmR is an accessory uridyltransferase essential for cytosolic survival and virulence

D. Pensinger, K. V. Gutierrez, H. B. Smith, W. J. B. Vincent, D. M. Stevenson, K. A. Black, K. M. Perez-Medina, J. P. Dillard, K. Y. Rhee, D. Amador-Noguez, T. N. Huynh, J.-D. Sauer

This study identifies GlmR as an accessory uridyltransferase essential for Listeria monocytogenes cytosolic survival and virulence by synthesizing UDP-GlcNAc.

bioRxiv · Oct 27, 2021 · PreprintMicrobiology

Listeria monocytogenes MenI encodes a DHNA-CoA thioesterase necessary for menaquinone biosynthesis, cytosolic survival, and virulence

H. B. Smith, T. L. Li, M. K. Liao, G. Y. Chen, Z. Guo, J.-D. Sauer

bioRxiv · Dec 21, 2020Microbiology

FplA From Fusobacterium nucleatum Is A Type Vd Autotransporter Phospholipase With A Proposed Role In Altered Host Signaling And Evasion Of Autophagy

M. A. Casasanta, C. C. Yoo, H. B. Smith, A. J. Duncan, K. Cochrane, A. C. Varano, E. Allen-Vercoe, D. J. Slade

This paper characterizes FplA, a Type Vd autotransporter phospholipase from F. nucleatum, showing its potential role in modulating host signaling and evading autophagy.

bioRxiv · May 10, 2017Microbiology