Author

H. Hornegger

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Cell Biology· 1 Plant Biology· 1

Signature Assays, Organisms & Methods

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Assay:proteomics· 3 Research Focus:chromatin & epigenetic regulation· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Approach:comparative / phylogenetic analysis· 1 Organism:plant (other)· 1

Frequent Co-Authors

T. Clausen· 2 shared A. Muratovic· 1 shared A. S. Anisimova· 1 shared B. R. Burgeois· 1 shared D. B. Grabarczyk· 1 shared D. Haselbach· 1 shared E. G. Karagoz· 1 shared E. Karagoez· 1 shared

Activity by Year

2022-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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2 shared papersCell Biology

T. Clausen

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Author profile →

3 papers

Recent·Most cited

Guardian ubiquitin E3 ligases target cancer-associated APOBEC3 deaminases for degradation to promote human genome integrity.

I. Schwartz, V. Budroni, M. Meyenberg, H. Hornegger, K. Hacker, S. Schwartz, Z. Hodakova, D. B. Grabarczyk, J. Ehrmann, S. Scinicariello, D. Haselbach, J. Menche, T. Clausen, E. Karagoez, G. A. Versteeg

The paper identifies UBR4, UBR5, and HUWE1 as E3 ligases that degrade cancer-associated APOBEC3 proteins to prevent genome mutagenesis.

bioRxiv · Apr 23, 2024Cell Biology

IGF2BP1 phosphorylation regulates ribonucleoprotein condensate formation by impairing low-affinity protein and RNA interactions

H. Hornegger, A. Muratovic, A. S. Anisimova, B. R. Burgeois, E. Spinetti, R. Covino, T. Madl, G. E. Karagoz

This study shows that phosphorylation of IGF2BP1 at S181 and Y396 modulates RNP condensate formation by altering low-affinity interactions with RNA and protein partners.

bioRxiv · Dec 5, 2023 · PreprintBiochemistry

Shuffled ATG8 interacting motifs form an ancestral bridge between UFMylation and C53-mediated autophagy

L. Picchianti, V. Sanchez de Medina Hernandez, N. Zhan, N. A. T. Irwin, M. Stephani, H. Hornegger, R. Beveridge, J. Sawa-Makarska, T. Lendl, N. Grujic, S. Martens, T. A. Richards, T. Clausen, S. Ramundo, E. G. Karagoz, Y. Dagdas

The paper shows that non-canonical shuffled ATG8 interacting motifs in C53 link UFMylation and autophagy, revealing an ancestral regulatory mechanism for ER homeostasis.

bioRxiv · Apr 26, 2022Plant Biology