Y. Dagdas

Metabolic enzymes moonlight as selective autophagy receptors to protect plants against viral-induced cellular damage

This study shows that metabolic enzymes act as autophagy receptors in plants to degrade defense executors during viral infection, revealing autophagy as a tolerance pathway rather than an antiviral defense.

ATG8ylation of vacuolar membrane protects plants against cell wall damage

This study identifies a vacuolar quality control pathway in plants that uses ATG8ylation to protect vacuolar integrity following cell wall damage.

The Arabidopsis thaliana TRAPPIII subunit AtTRAPPC8/AtTRS85 is involved in ER functioning and autophagy

This study identifies Arabidopsis thaliana TRAPPC8's role in ER function and autophagy, showing defects in morphology, ER stress, and lipid homeostasis in mutants.

ATG8 delipidation is not universally critical for autophagy in plants

This study shows that ATG8 delipidation is essential for autophagy in Chlamydomonas but dispensable in Arabidopsis, highlighting evolutionary divergence in autophagy mechanisms.

Autophagy restricts fungal accommodation in the roots of Arabidopsis thaliana

This study shows autophagy limits fungal colonization in Arabidopsis roots by restricting cell death induced by S. indica effectors.

A RabGAP-Rab GTPase pair regulates plant autophagy and immunity

This study identifies Rab3GAPL as a regulator of plant autophagy and immunity by modulating Rab8a and ATG8 interactions.

PAT mRNA decapping factors function specifically and redundantly during development in Arabidopsis

The paper investigates the roles of PAT mRNA decapping factors in Arabidopsis development, showing specific and redundant functions in growth and leaf morphology.

Shuffled ATG8 interacting motifs form an ancestral bridge between UFMylation and C53-mediated autophagy

The paper shows that non-canonical shuffled ATG8 interacting motifs in C53 link UFMylation and autophagy, revealing an ancestral regulatory mechanism for ER homeostasis.

Plant autophagosomes mature into amphisomes prior to their delivery to the central vacuole

The paper identifies CFS1 as an autophagy adaptor that connects autophagosomes with the ESCRT-I component VPS23 to form amphisomes, facilitating vacuolar delivery in plants.

Autophagy promotes programmed cell death and corpse clearance in specific cell types of the Arabidopsis root cap

A NET4-RabG3 couple mediate the link between actin and the tonoplast and is essential for normal actin cytoskeletal remodelling in stomatal closure to flg22

This study identifies NET4-RABG3b interaction as essential for actin cytoskeletal remodelling during stomatal closure in response to microbial patterns.

Bacterial-type plant ferroxidases tune local phosphate sensing in root development

The paper shows that bacterial-type ferroxidases in Arabidopsis thaliana modulate phosphate sensing in roots by regulating iron homeostasis and growth under phosphate limitation.

Host-interactor screens of Phytophthora infestans RXLR proteins reveal vesicle trafficking as a major effector-targeted process

This study identifies host processes targeted by Phytophthora infestans RXLR effectors through protein-protein interaction screens, revealing vesicle trafficking as a major effector-targeted process.

A cross-kingdom conserved ER-phagy receptor maintains endoplasmic reticulum homeostasis during stress

The paper identifies C53 as a conserved ER-phagy receptor that links autophagy with ribosome-associated quality control during ER stress in plants and mammals.

The Irish potato famine pathogen subverts host vesicle trafficking to channel starvation-induced autophagy to the pathogen interface

This study shows how the potato blight pathogen P. infestans uses the effector PexRD54 to redirect host autophagy towards the pathogen interface, benefiting the pathogen.

mRNA decapping machinery targets LBD3/ASL9 transcripts to authorize developmental reprogramming in Arabidopsis

The paper shows that mRNA decapping regulates LBD3/ASL9 transcript levels to balance cytokinin/auxin responses during developmental reprogramming in Arabidopsis.

EXO70D isoforms mediate selective autophagic degradation of Type-A ARR proteins to regulate cytokinin sensitivity

Autophagy mediates temporary reprogramming and dedifferentiation in plant somatic cells

This study shows autophagy is essential for temporary reprogramming and dedifferentiation in plant somatic cells, enabling adaptation to environmental changes and cellular reprogramming.

N-terminal β-strand underpins biochemical specialization of an ATG8 isoform

The paper identifies the N-terminal β-strand and a single amino acid polymorphism as key determinants of binding specificity for the ATG8 isoform in potato, shaping interactions with PexRD54 and other plant proteins.

Peripheral infrastructure vectors and an extended set of plant parts for the modular cloning system

The paper introduces 80 new phytobricks and peripheral infrastructure for the Modular Cloning system to enhance its versatility in plant synthetic biology.