Author

H. R. Kim

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Bioengineering· 1 Biophysics· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:database / resource· 1 Research Focus:development & morphogenesis· 1

Frequent Co-Authors

I. Lee· 2 shared K. Kim· 2 shared A. Chyong· 1 shared A. K. Shukla· 1 shared A. Kellner· 1 shared A. Ruggieri· 1 shared A. Srivastava· 1 shared C. C. Porter· 1 shared

Activity by Year

2019-2020 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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2 shared papersMicrobiology

I. Lee

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Human reference gut microbiome comprising 5,414 prokaryotic species, including newly assembled genomes from under-represented Asian metagenomes

C. Y. Kim, M. Lee, S. Yang, K. Kim, D. Yong, H. R. Kim, I. Lee

The paper expands the human gut microbiome reference database by incorporating newly assembled genomes from under-represented Asian populations, improving taxonomic and functional classification and revealing associations with autoimmunity.

bioRxiv · Nov 9, 2020Microbiology

Optical Control of Cytokine Signaling via Bioinspired, Polymer-Induced Latency

L. A. Perdue, P. Do, C. David, A. Chyong, A. Kellner, A. Ruggieri, H. R. Kim, K. Salaita, G. B. Lesinski, C. C. Porter, E. C. Dreaden

This paper develops a method to control cytokine signaling using light-activated polymers that induce latency and release cytokines on demand.

bioRxiv · Feb 13, 2020Bioengineering

Single-cell transcriptome analysis reveals TOX as a promoting factor for T-cell exhaustion and a predictor for anti-PD1 responses in human cancer

K. Kim, S. Park, S. Y. Park, G. Kim, S. M. Park, J.-W. Cho, D. H. Kim, Y. M. Park, Y. W. Koh, H. R. Kim, S.-J. Ha, I. Lee

The paper identifies TOX as a factor promoting T-cell exhaustion and predicts its role in anti-PD1 therapy outcomes using single-cell transcriptome data from cancer patients.

bioRxiv · Dec 3, 2019 · PreprintCancer Biology

The investigation of the role of VHL-HIF signaling in DNA repair and apoptosis in zebrafish

H. R. Kim, K. Santhakumar, E. Markham, D. Baldera, H. E. Bryant, S. F. El-Khamisy, F. J. van Eeden

This study investigates the role of VHL-HIF signaling in DNA repair and apoptosis in zebrafish, finding that HIF activation suppresses DNA repair defects and apoptosis in vll and brca2 mutants.

bioRxiv · Sep 18, 2019Cancer Biology

Conformational sensors and domain-swapping reveal structural and functional differences between β-arrestin isoforms

E. Ghosh, H. Dwivedi, M. Baidya, A. Srivastava, P. Kumari, T. Stepniewski, H. R. Kim, M.-H. Lee, J. v. Gastel, M. Chaturvedi, D. Roy, S. Pandey, J. Maharana, R. Guixa-Gonzalez, L. M. Luttrell, , A. K. Shukla

The paper identifies structural differences between β-arrestin isoforms using conformational sensors and domain-swapping, linking these differences to their distinct functional outcomes in GPCR signaling.

bioRxiv · Aug 5, 2019Biophysics