Author

Hui Xu

East Carolina University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Same name, identified by ORCID

Biology Disciplines

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Microbiology· 2 Neuroscience· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:bacteria (other)· 2 Organism:human· 2 Research Focus:cell type annotation· 1 Assay:cryo-EM· 1 Research Focus:differential expression· 1 Assay:imaging· 1 Approach:microscopy & imaging analysis· 1

Frequent Co-Authors

Gary E. GibsoniD· 2 shared Huan‐Lian Chen· 2 shared Huaxin YuiD· 2 shared Jian YueiD· 2 shared Jun LiuiD· 2 shared MD A. MOTALEBiD· 2 shared Md Khalesur Rahman· 2 shared Wangbiao GuoiD· 2 shared

Activity by Year

2019-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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2 shared papersNeuroscience

Gary E. GibsonORCID

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Author profile →

4 papers

Recent·Most cited

In situ cryo-EM reveals how a flagellar motor transmits high torque

Jian Yue, Wangbiao Guo, Md Khalesur Rahman, Hui Xu, Md Samiul Haque, Aaron Ye, Huaxin Yu, Jun Liu, MD A. MOTALEB

This study uses in situ cryo-EM to reveal how the flagellar motor in Borrelia burgdorferi transmits high torque through mechanical coupling and a split washer-shaped FrbA brace.

bioRxiv · Oct 15, 2026 · PreprintMicrobiology

In-situ structure of the flagellar export apparatus in Borrelia burgdorferi

Jian Yue, Akarsh Manne, Wangbiao Guo, Huaxin Yu, Jiaqi Wang, Md Khalesur Rahman, Kathryn Lees, Hui Xu, Jack M. Botting, Md A. Motaleb, Jun Liu

This study uses cryo-EM to determine the structure of the flagellar export apparatus in Borrelia burgdorferi, revealing its assembly mechanism and role in substrate translocation.

bioRxiv · May 13, 2026 · PreprintMicrobiology

Selective linkage of mitochondrial enzymes to intracellular calcium stores differs between human induced pluripotent stem cells, neural stem cells and neurons

Huan‐Lian Chen, Ankita Thakkar, Abigail C. Cross, Hui Xu, Aiqun Li, Daniel J Paull, Scott Noggle, Laken Kruger, Travis T. Denton, Gary E. Gibson

The paper examines how ER/mitochondrial coupling changes during human neuronal development and links it to Alzheimer's disease pathology.

Journal of Neurochemistry · Aug 31, 2020Peer-reviewedNeuroscience

Succinylation Links Metabolic Reductions to Amyloid and Tau Pathology

Yun Yang, Vı́ctor Tapias, Diana M. Acosta, Hui Xu, Huan‐Lian Chen, Ruchika P. Bhawal, Elizabeth Anderson, Elena Ivanova, Hening Lin, Botir T. Sagdullaev, William L. Klein, Kirsten L. Viola, Sam Gandy, Vahram H. Haroutunian, M. Flint Beal, , Gary E. Gibson

This study identifies lysine succinylation as a post-translational modification linked to amyloid and tau pathology in Alzheimer's disease through human brain and mouse model analyses.

bioRxiv · Sep 16, 2019 · PreprintNeuroscience