Author

I. P. MacFawn

Every paper listing this name carries an ORCID.

Identified by ORCID

I. P. MacFawniD1 paper · University of Pittsburgh

Biology Disciplines

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Cancer Biology· 2 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

Tullia Carmela BrunoiD· 3 shared Riyue BaoiD· 2 shared A. Carolina TufinoiD· 1 shared Abishek Balachandra VaidyaiD· 1 shared Adam C. OlsoniD· 1 shared Alexander TepperiD· 1 shared Alexandra TabachnikovaiD· 1 shared Alexandros D. PolydoridesiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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3 shared papersCancer Biology

Tullia Carmela BrunoORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Dendritic cells type 1 control the formation, maintenance, and function of tertiary lymphoidstructures in cancer

Raphaël Mattiuz, Jesse Boumelha, Emmanouil Aerakis, Jessica Le Bérichel, Pauline Hamon, László Halász, Abishek Balachandra Vaidya, Brian Y. Soong, Emir Radkevich, Hye Mi Kim, Matthew D. Park, Romain Donné, Leanna Troncoso, Rachel A. Kaplan, Clotilde Hennequin, , Miriam Mérad

This study identifies the role of mature dendritic cells type 1 in forming, maintaining, and functioning tertiary lymphoid structures in cancer.

Science · Jul 16, 2026Peer-reviewedImmunology

Stromal mediated DNA damage promotes high grade serous ovarian cancer initiation

Geyon L. Garcia, Taylor J. Orellana, Grace Gorecki, Leonard G. Frisbie, Roja Baruwal, Swathi Suresh, Ester Goldfeld, Ian Beddows, I. P. MacFawn, Ananya K. Britt, Macy M. Hale, Amal Taher Elhaw, Brian Robert Isett, Nadine Hempel, Riyue Bao, , Lan Gardner Coffman

This study identifies high-risk mesenchymal stem cells (hrMSCs) that drive DNA damage and promote high-grade serous ovarian cancer initiation in fallopian tube epithelium.

Cancer Discovery · Mar 14, 2025Peer-reviewedCancer Biology

Immunocompetent murine model of Ewing sarcoma reveals role for TGFβ inhibition to enhance immune infiltrates in Ewing tumors during radiation

Jessica D. Daley, Elina Mukherjee, A. Carolina Tufino, Nathanael G. Bailey, Shanthi Bhaskar, Nivitha Periyapatna, Ian MacFawn, Sheryl R. Kunning, Cynthia S. Hinck, Tullia Carmela Bruno, Adam C. Olson, Linda M. McAllister‐Lucas, Andrew P. Hinck, Kristine L. Cooper, Riyue Bao, , Kelly M. Bailey

The paper develops an immunocompetent mouse model of Ewing sarcoma to show that TGFβ inhibition enhances immune infiltration and reduces metastasis during radiation therapy.

bioRxiv · May 7, 2024 · PreprintCancer Biology