Author

J. C. Horvat

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Immunology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Assay:proteomics· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Assay:metabolomics· 1

Frequent Co-Authors

P. A. Wark· 3 shared P. M. Hansbro· 3 shared P. S. Pathinayake· 2 shared A. C.-Y. Hsu· 1 shared A. F. Faiz· 1 shared A. Reid· 1 shared A. T. Reid· 1 shared A. Vaughan· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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3 shared papersPhysiology

P. A. Wark

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Fecal microbial transfer and complex carbohydrates mediate protection against COPD

K. F. Budden, S. Shukla, K. L. Bowerman, S. L. Gellatly, D. L. A. Wood, N. Lachner, S. Idrees, V. Patel, A. F. Faiz, S. F. Rehman, C. Donovan, C. Alemao, S. Shen, K. S. Vanka, J. Mason, , P. M. Hansbro

This study shows that fecal microbial transfer and complex carbohydrates can reduce COPD symptoms in mice and humans, linking gut microbiota to disease progression.

bioRxiv · Oct 16, 2023 · PreprintPhysiology

Single cell RNA-seq identifies inflammation-induced loss of CFTR-expressing airway ionocytes in non-eosinophilic asthma

L. Chen, G. A. Hoefel, P. S. Pathinayake, A. Reid, C. Kelly, T. HuiYing, R. Y. Kim, P. M. Hansbro, S. L. Brody, P. S. Foster, J. C. Horvat, C. Riveros, P. A. Wark, G. E. Kaiko

This study identifies inflammation-induced loss of CFTR-expressing ionocytes in non-eosinophilic asthma using single-cell RNA-seq and confirms it in human and murine models.

bioRxiv · Apr 26, 2022 · PreprintCell Biology

SARS-CoV-2 Spike protein promotes hyper-inflammatory response that can be ameliorated by Spike-antagonistic peptide and FDA-approved ER stress and MAP kinase inhibitors in vitro

A. C.-Y. Hsu, G. Wang, A. T. Reid, P. C. Veerati, P. S. Pathinayake, K. Daly, J. R. Mayall, P. M. Hansbro, J. C. Horvat, F. Wang, P. A. Wark

This study shows that SARS-CoV-2 spike protein induces inflammation and epithelial damage, which can be reduced by an antagonistic peptide and FDA-approved drugs.

bioRxiv · Sep 30, 2020 · PreprintImmunology