Author

J. C. Wolters

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 3 Biochemistry· 1 Cancer Biology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 6 Organism:yeast· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Organism:mouse· 2 Assay:proteomics· 2 Approach:biophysical modeling· 1

Frequent Co-Authors

A. Steen· 2 shared B. M. Bakker· 2 shared D.-J. Reijngoud· 2 shared F. Abegaz· 2 shared M. A. Vieira-Lara· 2 shared P. R. Onck· 2 shared T. H. van Dijk· 2 shared A. C. Reijne· 1 shared

Activity by Year

2021-2023 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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2 shared papersCell Biology

A. Steen

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

The Hansenula polymorpha Mitochondrial Carrier Family proteins Mir1 and Aac2 are dually localized at peroxisomes and mitochondria

M. P. Pedersen, J. C. Wolters, R. de Boer, A. M. Krikken, I. J. van der Klei

This study identifies dual localization of mitochondrial carrier proteins Aac2 and Mir1 to peroxisomes and mitochondria in Hansenula polymorpha, revealing requirements for Pex3 and Pex19 in peroxisomal targeting.

bioRxiv · Nov 15, 2023 · PreprintCell Biology

Nucleoporin Nsp1 surveils the phase state of FG-Nups

T. A. Otto, T. Bergsma, M. Dekker, S. Mouton, P. Gallardo, J. C. Wolters, A. Steen, P. R. Onck, L. L. Veenhoff

The paper shows that Nsp1 modulates FG-Nup phase separation and its loss mimics aging phenotypes in yeast.

bioRxiv · Mar 31, 2023Cell Biology

Age and diet modulate the insulin-sensitizing effects of exercise: a tracer-based oral glucose tolerance test

M. A. Vieira-Lara, A. C. Reijne, S. Koshian, J. Ciapaite, F. Abegaz, A. Talarovicova, T. H. van Dijk, C. J. Versloot, R. H. J. Bandsma, J. C. Wolters, A. K. Groen, D.-J. Reijngoud, G. van Dijk, B. M. Bakker

This study shows that exercise improves age-related decline in insulin sensitivity in mice, but only when combined with a healthy diet.

bioRxiv · Mar 18, 2023Physiology

Ultrasensitive detection of circulating LINE-1 ORF1p as a specific multi-cancer biomarker

M. S. Taylor, W. Connie, P. C. Fridy, S. J. Zhang, Y. Senussi, J. C. Wolters, W.-C. Cheng, J. Heaps, B. D. Miller, K. Mori, L. Cohen, H. Jiang, K. R. Molloy, B. L. Norden, B. T. Chait, , O. H. Yilmaz

This study develops ultrasensitive assays to detect ORF1p in plasma, showing its potential as a multi-cancer biomarker for early detection and monitoring.

bioRxiv · Jan 25, 2023 · PreprintCancer Biology

Nuclear transport under stress phenocopies transport defects in models of C9Orf72 ALS

M. F. Semmelink, H. Jafarinia, J. C. Wolters, T. Gheorghe, S. N. Mouton, A. Steen, P. R. Onck, L. M. Veenhoff

This study shows polyPR directly affects nuclear transport via NTRs, while polyGA impacts cellular energy state, leading to similar transport defects as stress conditions.

bioRxiv · Apr 13, 2022 · PreprintCell Biology

Age-related susceptibility to insulin resistance is due to a combination of CPT1B decline and lipid overload

M. A. Vieira-Lara, M. B. Dommerholt, W. Zhang, M. Blankestijn, J. C. Wolters, F. Abegaz, Y. van der Veen, T. H. van Dijk, R. van Os, D.-J. Reijngoud, J. W. Jonker, J. K. Kruit, B. M. Bakker

This study shows that age-related insulin resistance in mice is caused by both reduced CPT1B and lipid overload, not just mitochondrial dysfunction or diet alone.

bioRxiv · Feb 4, 2021Biochemistry