Author

V. Graziano

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Assay:proteomics· 1 Assay:spatial transcriptomics· 1

Frequent Co-Authors

A. Dannhorn· 1 shared A. G. Schuller· 1 shared A. O. Kolawole· 1 shared B. P. Kaistha· 1 shared C. Wilen· 1 shared C. Wobus· 1 shared D. I. Jodrell· 1 shared E. A. Kennedy· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperCancer Biology

A. Dannhorn

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2 papers

Recent·Most cited

Defining the spatial distribution of extracellular adenosine revealed a myeloid-dependent immunosuppressive microenvironment in pancreatic ductal adenocarcinoma

V. Graziano, A. Dannhorn, H. Hulme, K. Williamson, H. Buckley, S. A. Karim, S. Y. Lee, B. P. Kaistha, S. Islam, J. E. D. Thaventhiran, F. M. Richards, R. Goodwin, R. Brais, J. P. Morton, S. J. Dovedi, , D. I. Jodrell

This study shows that extracellular adenosine promotes an immunosuppressive microenvironment in PDAC by enhancing myeloid cell infiltration and resistance to immunotherapy, and that blocking adenosine pathway components improves therapeutic outcomes.

bioRxiv · May 24, 2022Cancer Biology

CD300lf is the primary physiologic receptor of murine norovirus but not human norovirus

V. Graziano, F. C. Walker, E. A. Kennedy, J. Wei, K. Ettayebi, M. Simoes, R. Filler, E. Hassan, L. L. Hsieh, A. O. Kolawole, C. Wobus, L. C. Lindesmith, R. S. Baric, M. Estes, R. C. Orchard, , C. Wilen

This paper identifies CD300lf as the primary receptor for murine norovirus in vivo but shows it is not used by human norovirus.

PLOS Pathogens · Apr 6, 2020Peer-reviewedMicrobiology