Author

J. M. Murray

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 5 Biochemistry· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 6 Research Focus:cell signaling & trafficking· 3 Research Focus:development & morphogenesis· 3 Research Focus:host-pathogen & immune response· 3 Organism:human· 3 Assay:imaging· 2 Organism:yeast· 2 Assay:cryo-EM· 1

Frequent Co-Authors

K. Hu· 5 shared J. Liu· 4 shared L. F. Arias Padilla· 3 shared E. Nagayasu· 2 shared I. F. Tengganu· 2 shared J. M. Leung· 2 shared L. Zhou· 2 shared P. Schellenberger· 2 shared

Activity by Year

2017-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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5 shared papersCell Biology

K. Hu

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Author profile →

7 papers

Recent·Most cited

The initiation and early development of the tubulin-containing cytoskeleton in the human parasite Toxoplasma gondii

L. F. Arias Padilla, J. M. Murray, K. Hu

This study examines the development of tubulin-containing structures in Toxoplasma gondii using advanced imaging techniques, revealing distinct developmental patterns and symmetry changes.

bioRxiv · Nov 3, 2023Cell Biology

The cortical microtubules of Toxoplasma gondii underlie the helicity of parasite movement

I. F. Tengganu, L. F. Arias Padilla, J. Munera Lopez, J. Liu, P. T. Brown, J. M. Murray, K. Hu

This study investigates the role of cortical microtubules in Toxoplasma gondii motility, showing that their destabilization reduces helical movement without affecting speed or invasion/egress.

bioRxiv · Apr 23, 2023Cell Biology

An apical protein, Pcr2, is required for persistent movement by the human parasite Toxoplasma gondii

J. M. Lopez, I. F. Tengganu, J. Liu, J. M. Murray, L. F. Arias Padilla, Y. Zhang, P. T. Brown, L. Florens, K. Hu

This study identifies Pcr2 as a critical protein for movement and invasion in Toxoplasma gondii, showing that its absence impairs egress and tissue destruction.

bioRxiv · May 20, 2022Cell Biology

Cryo-EM structure of the Smc5/6 holo-complex

S. T. Hallett, I. Campbell Harry, P. Schellenberger, L. Zhou, N. B. Cronin, J. Baxter, T. J. Etheridge, J. M. Murray, A. W. Oliver

The paper reports the cryo-EM structure of the budding yeast Smc5/6 holo-complex, revealing its architecture and interactions between subunits.

bioRxiv · Nov 25, 2021Biochemistry

Nse5/6 is a negative regulator of the ATPase activity of the Smc5/6 complex

S. T. Hallett, P. Schellenberger, L. Zhou, F. Beuron, E. Morris, J. M. Murray, A. Oliver

This study identifies Nse5/6 as a negative regulator of Smc5/6 ATPase activity in S. cerevisiae by showing it suppresses ATP turnover through binding to the complex head-end.

bioRxiv · Feb 12, 2021Biochemistry

A doublecortin-domain protein of Toxoplasma and its orthologues bind to and modify the structure and organization of tubulin polymers

J. M. Leung, E. Nagayasu, Y.-C. Hwang, J. Liu, P. Pierce, I. Q. Phan, R. A. Prentice, J. M. Murray, K. Hu

This study identifies TgDCX, a Toxoplasma protein that binds and modifies tubulin polymers, enabling curved structures critical for parasite invasion.

bioRxiv · Jan 15, 2020Cell Biology

Stability and function of a putative microtubule organizing center in the human parasite Toxoplasma gondii

J. M. Leung, Y. He, F. Zhang, Y.-C. Hwang, E. Nagayasu, J. Liu, J. M. Murray, K. Hu

This study investigates the role of the apical polar ring in Toxoplasma gondii by analyzing KinesinA and APR1, showing its structural importance for microtubule organization and parasite function.

bioRxiv · Mar 14, 2017Cell Biology