Author

J. Michelle Lee

Arc Research Institute

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Immunology· 2

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Research Focus:metabolism & bioenergetics· 1

Frequent Co-Authors

Jacqueline A. CarozzaiD· 2 shared Lingyin LiiD· 2 shared Valentino SudaryoiD· 2 shared Anthony F. CordovaiD· 1 shared Courtney KernickiD· 1 shared Dayanne R. CarvalhoiD· 1 shared Gabriel Grenot· 1 shared Gemini M. Skariah· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersImmunology

Jacqueline A. CarozzaORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

ENPP1 buffers extracellular cGAMP in brown adipose tissue to limit insulin resistance

Songnan Wang, Yingjie Guo, Weidong An, J. Michelle Lee, Yu Li, Valentino Sudaryo, Jacqueline A. Carozza, Gabriel Grenot, Gemini M. Skariah, Saranya Chidambaranathan Reghupaty, Sonny Young, Xiaochen Bai, Katrin J. Svensson, Lingyin Li

This study shows that the ENPP1 K173Q variant reduces cGAMP hydrolysis, leading to increased extracellular cGAMP and insulin resistance in brown adipose tissue.

Cell Reports · Sep 15, 2026Peer-reviewedImmunology

Toxicity of extracellular cGAMP and its analogs to T cells is due to SLC7A1-mediated import

Valentino Sudaryo, Dayanne R. Carvalho, Jacqueline A. Carozza, Xujun Cao, Courtney Kernick, Anthony F. Cordova, J. Michelle Lee, Theodore L. Roth, Lingyin Li

The paper identifies SLC7A1 as the transporter for cGAMP and its analogs in T cells, showing that targeting this transporter can reduce toxicity without affecting arginine transport.

Cell Reports · Jun 22, 2026Peer-reviewedImmunology