Author

Valentino Sudaryo

Arc Research InstituteORCID 0000-0002-5816-9955Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Research Focus:metabolism & bioenergetics· 1

Frequent Co-Authors

J. Michelle Lee· 2 shared Jacqueline A. CarozzaiD· 2 shared Lingyin LiiD· 2 shared Anthony F. CordovaiD· 1 shared Courtney KernickiD· 1 shared Dayanne R. CarvalhoiD· 1 shared Gabriel Grenot· 1 shared Gemini M. Skariah· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersImmunology

J. Michelle Lee

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2 papers

Recent·Most cited

ImmunologyCell ReportsPeer-reviewedSep 15, 2026

ENPP1 buffers extracellular cGAMP in brown adipose tissue to limit insulin resistance

Songnan Wang, Yingjie Guo, Weidong An…·Lingyin Li

This study shows that the ENPP1 K173Q variant reduces cGAMP hydrolysis, leading to increased extracellular cGAMP and insulin resistance in brown adipose tissue.

DOI 10.1016/j.celrep.2026.118009

mouseexperimental assay

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ImmunologyCell ReportsPeer-reviewedJun 22, 2026

Toxicity of extracellular cGAMP and its analogs to T cells is due to SLC7A1-mediated import

Valentino Sudaryo, Dayanne R. Carvalho, Jacqueline A. Carozza…·Lingyin Li

The paper identifies SLC7A1 as the transporter for cGAMP and its analogs in T cells, showing that targeting this transporter can reduce toxicity without affecting arginine transport.

2 citations

mousehuman

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