Author

J. R. Kent

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Approach:comparative / phylogenetic analysis· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Research Focus:metabolism & bioenergetics· 1

Frequent Co-Authors

M. L. L. Madariaga· 2 shared A. A. I. Deik· 1 shared A. Ali· 1 shared A. Muir· 1 shared B. I. Reinfeld· 1 shared C. A. Lewis· 1 shared C. A. Troxell· 1 shared C. B. Clish· 1 shared

Activity by Year

2023-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersImmunology

M. L. L. Madariaga

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2 papers

Recent·Most cited

Mutability and hypermutation antagonize immunoglobulin codon optimality

J. J. McGrath, J. Park, C. A. Troxell, J. C. Chervin, L. Li, J. R. Kent, S. Changrob, Y. Fu, M. Huang, N.-Y. Zheng, G. D. Wilbanks, S. A. Nelson, J. Sun, G. Inghirami, M. L. L. Madariaga, , P. C. Wilson

The paper examines how immunoglobulin codon optimality interacts with mutability and hypermutation in antibody evolution, finding that codon deoptimization correlates with expression loss and is constrained by selective pressures.

bioRxiv · Mar 13, 2024Immunology

Metabolite profiling of human renal cell carcinoma reveals tissue-origin dominance in nutrient availability

K. L. Abbott, A. Ali, B. I. Reinfeld, A. A. I. Deik, S. Subudhi, M. D. Landis, R. A. Hongo, K. L. Young, T. Kunchok, C. S. Nabel, K. D. Crowder, J. R. Kent, M. L. L. Madariaga, R. K. Jain, K. E. Beckermann, , M. G. Vander Heiden

This study profiles metabolites in renal cell carcinoma tissue and fluid to show that nutrient availability is more influenced by tissue-specific factors than tumor-driven changes.

bioRxiv · Dec 24, 2023Cancer Biology