Author

C. S. Nabel

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 2 Research Focus:cell signaling & trafficking· 1 Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:development & morphogenesis· 1 Assay:DNA methylation· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

C. A. Lewis· 2 shared M. G. Vander Heiden· 2 shared A. A. I. Deik· 1 shared A. Ali· 1 shared A. L. Tang· 1 shared A. Mehta· 1 shared A. Muir· 1 shared A. Shih· 1 shared

Activity by Year

2021-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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2 shared papersCancer Biology

C. A. Lewis

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Metabolite profiling of human renal cell carcinoma reveals tissue-origin dominance in nutrient availability

K. L. Abbott, A. Ali, B. I. Reinfeld, A. A. I. Deik, S. Subudhi, M. D. Landis, R. A. Hongo, K. L. Young, T. Kunchok, C. S. Nabel, K. D. Crowder, J. R. Kent, M. L. L. Madariaga, R. K. Jain, K. E. Beckermann, , M. G. Vander Heiden

This study profiles metabolites in renal cell carcinoma tissue and fluid to show that nutrient availability is more influenced by tissue-specific factors than tumor-driven changes.

bioRxiv · Dec 24, 2023Cancer Biology

Spatial analysis of human lung cancer reveals organized immune hubs enriched for stem-like CD8 T cells and associated with immunotherapy response

J. H. Chen, L. T. Nieman, M. Spurrell, V. Jorgji, P. M. Richieri, K. H. Xu, R. Madhu, M. Parikh, I. Zamora, A. Mehta, C. S. Nabel, S. S. Freeman, J. D. Pirl, C. Lu, C. B. Meador, , N. Hacohen

The paper identifies immune hubs in lung cancer that are associated with better responses to PD-1-blockade immunotherapy and contain stem-like CD8 T cells.

bioRxiv · Apr 4, 2023Immunology

Nucleotide imbalance decouples cell growth from cell proliferation

F. F. Diehl, T. P. Miettinen, R. Elbashir, C. S. Nabel, S. R. Manalis, C. A. Lewis, M. G. Vander Heiden

The paper shows that nucleotide imbalances during S phase disrupt DNA replication and cell proliferation, requiring replication stress signaling for survival.

bioRxiv · Dec 6, 2021Cell Biology