Author

B. I. Reinfeld

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Biochemistry· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:human· 3 Research Focus:metabolism & bioenergetics· 3 Research Focus:cancer & tumor microenvironment· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Assay:imaging· 1

Frequent Co-Authors

W. K. Rathmell· 4 shared J. C. Rathmell· 3 shared K. E. Beckermann· 3 shared A. Ali· 2 shared A. Muir· 2 shared C. A. Lewis· 2 shared J. E. Bader· 2 shared K. L. Young· 2 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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4 shared papersCancer Biology

W. K. Rathmell

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Author profile →

4 papers

Recent·Most cited

Metabolite profiling of human renal cell carcinoma reveals tissue-origin dominance in nutrient availability

K. L. Abbott, A. Ali, B. I. Reinfeld, A. A. I. Deik, S. Subudhi, M. D. Landis, R. A. Hongo, K. L. Young, T. Kunchok, C. S. Nabel, K. D. Crowder, J. R. Kent, M. L. L. Madariaga, R. K. Jain, K. E. Beckermann, , M. G. Vander Heiden

This study profiles metabolites in renal cell carcinoma tissue and fluid to show that nutrient availability is more influenced by tissue-specific factors than tumor-driven changes.

bioRxiv · Dec 24, 2023Cancer Biology

PD-1 is induced on tumor-associated macrophages in obesity to directly restrain anti-tumor immunity

J. E. Bader, M. M. Wolf, M. Z. Madden, B. I. Reinfeld, E. N. Arner, E. S. Hathaway, K. K. Steiner, G. A. Needle, M. D. Landis, M. A. Cottam, X. Ye, A. Christofides, V. A. Boussiotis, S. M. Haake, K. E. Beckermann, , J. C. Rathmell

This study shows obesity induces PD-1 on tumor-associated macrophages, which suppresses anti-tumor immunity by altering metabolic and functional properties of these cells.

bioRxiv · Nov 12, 2022 · PreprintImmunology

A Family of Glycosylated Macrolides Selectively Target Energetic Vulnerabilities in Leukemia

B. J. Reisman, H. Guo, H. E. Ramsey, M. T. Wright, B. I. Reinfeld, P. B. Ferrell, G. A. Sulikowski, W. K. Rathmell, M. R. Savona, L. Plate, J. L. Rubinstein, B. O. Bachmann

This study identifies the mitochondrial ATP synthase as the target of apoptolidin family glycomacrolides and demonstrates their efficacy in suppressing leukemia progression.

bioRxiv · May 31, 2021Biochemistry

Cell Programmed Nutrient Partitioning in the Tumor Microenvironment

B. I. Reinfeld, M. Z. Madden, M. M. Wolf, A. Chytil, J. E. Bader, A. R. Patterson, A. S. Cohen, A. Ali, B. T. Do, C. A. Lewis, A. Muir, R. A. Hongo, K. L. Young, R. E. Brown, V. M. Todd, , W. K. Rathmell

The paper measures nutrient uptake in the tumor microenvironment using PET tracers and finds cancer cells prefer glutamine while myeloid cells consume most glucose.

bioRxiv · Aug 10, 2020 · PreprintCancer Biology