Keratin 19 interacts with GSK3β to regulate its nuclear accumulation and degradation of cyclin D3
P. Sharma, S. Tiufekchiev, V. Lising, S. W. Chung, J. S. Suk, B. M. Chung
This study shows that keratin 19 interacts with GSK3β to inhibit its nuclear accumulation and prevent cyclin D3 degradation, affecting cell proliferation and CDK4/6 inhibitor sensitivity.
bioRxiv · Jul 28, 2021Cancer Biology