Author

J.-R. Zhang

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Research Focus:benchmarking· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Approach:genetic perturbation / CRISPR· 1 Organism:non-human primate· 1

Frequent Co-Authors

J. Wang· 2 shared M. Ding· 2 shared Q. Jin· 2 shared X. Tian· 2 shared A. Domenech· 1 shared C. Gallay· 1 shared D. E. Briles· 1 shared H. An· 1 shared

Activity by Year

2016-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 26 mutual co-author links

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2 shared papersImmunology

J. Wang

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Pathogen Clearance-based Correlates of Immunoprotection Reveal Insightful Features of Vaccine Immunity

X. Tian, J. Wang, H. Chen, M. Ding, Q. Jin, J.-R. Zhang

This paper introduces a new vaccine evaluation system based on pathogen clearance and liver trapping to assess immunoprotective potential against bacterial infections.

bioRxiv · Aug 23, 2022Immunology

Potent Bacterial Vaccines Require FcγRIIB-mediated Pathogen Capture by Liver Sinusoidal Endothelium

J. Wang, H. An, M. Ding, Y. Liu, S. Wang, Q. Jin, H. Dong, X. Tian, J. Liu, J. Zhang, T. Zhu, J. Li, Z. Shao, D. E. Briles, H. Zheng, , J.-R. Zhang

This paper identifies FcγRIIB-mediated capture of antibody-coated bacteria by liver sinusoidal endothelial cells as a mechanism for superior vaccine efficacy.

bioRxiv · Jul 19, 2022Immunology

High-throughput CRISPRi phenotyping in Streptococcus pneumoniae identifies new essential genes involved in cell wall synthesis and competence development

X. Liu, C. Gallay, M. Kjos, A. Domenech, J. Slager, S. P. van Kessel, K. Knoops, R. A. Sorg, J.-R. Zhang, J.-W. Veening

This study uses CRISPRi to identify essential genes in S. pneumoniae, revealing roles in cell wall synthesis and competence development, and highlights potential antibiotic targets.

bioRxiv · Nov 17, 2016Microbiology