Z. Shao

LHP1 and INO80 cooperate with ethylene signaling for warm ambient temperature response by activating specific bivalent genes

This study shows that LHP1 and INO80 work with ethylene signaling to activate specific bivalent genes in response to warm temperatures in Arabidopsis.

A neutral process of genome reduction in marine bacterioplankton

The paper investigates genome reduction in marine bacterioplankton, finding that neutral processes like genetic drift, not streamlining selection, drive genome size reduction in the Roseobacter group.

Histone acetyltransferase HAF2 associates with PDC to control H3K14ac and H3K23ac in ethylene response

This study identifies HAF2 as a histone acetyltransferase that interacts with EIN2-C and PDC to regulate H3K14ac and H3K23ac in response to ethylene.

Siderophore synthetase-receptor gene coevolution reveals habitat- and pathogen-specific bacterial iron interaction networks

The paper develops a co-evolution algorithm to predict bacterial iron interaction networks based on siderophore synthetase-receptor gene pairs across Pseudomonas genomes, revealing habitat- and pathogen-specific interactions.

Spatiotemporal Profiling Unveiling the Cellular Organization Patterns and Local Protumoral Immune Microenvironment Remodeling in Early Lung Adenocarcinoma Progression

The paper uses spatial transcriptomics and single-cell RNA sequencing to identify cellular organization patterns and immune microenvironment changes in early lung adenocarcinoma progression.

Nuclear Pyruvate Dehydrogenase Complex Regulates Histone Acetylation and Transcriptional Regulation in the Ethylene Response

This study identifies the nuclear pyruvate dehydrogenase complex (PDC) as a key regulator of histone acetylation and transcription during ethylene response in plants.

MiR-574-5p activates human TLR8 to promote autoimmune signaling and lupus

This study shows miR-574-5p activates TLR8 to drive autoimmune signaling and lupus progression by enhancing cytokine production, STAT1 activation, and autoantigen generation.

SIDERITE: Unveiling Hidden Siderophore Diversity in the Chemical Space Through Digital Exploration

SIDERITE identifies new iron-binding molecules by analyzing chemical structures and confirming their iron-binding ability through experimental validation.

A vast repertoire of secondary metabolites influences community dynamics and biogeochemical processes in cold seeps

This study investigates secondary metabolites in cold seep microbiomes using metagenomic, metatranscriptomic, and metabolomic data, revealing diverse biosynthetic gene clusters and their potential ecological roles.

Quasi-Equilibrium State Based Quantification of Biological Macromolecules in Single-Molecule Localization Microscopy

This paper introduces a method to precisely quantify molecular stoichiometry in vivo using single-molecule localization microscopy by analyzing fluorophore detections during the quasi-equilibrium state.

A comprehensive catalog with 100 million genes and 3,000 metagenome-assembled genomes from global cold seep sediments

The paper constructs a comprehensive gene and genome catalog from cold seep sediments, revealing novel microbial species and a large fraction of uncharacterized genes.

A Non-Canonical IRAK Signaling Pathway Triggered by DNA Damage

The paper identifies a non-canonical IRAK signaling pathway triggered by DNA damage that promotes anti-apoptosis and is activated by ionizing radiation and genotoxic therapies.

The first host-associated anaerobic isolate of Psychrilyobacter provides insights into its potential roles in the abalone gut

The paper isolates the first host-associated Psychrilyobacter strain from abalone gut and identifies its functional roles in host metabolism and health.

Unexpected genetic and microbial diversity for arsenic cycling in deep sea cold seep sediments

The paper analyzes metagenomic and metatranscriptomic data from cold seeps to identify As-cycling genes and microbes, revealing unexpected diversity and functional roles in arsenic transformation.

Spatial Localization Ability of Planarians Identified Through the Light Maze Paradigm

This paper demonstrates that planarians can navigate to a previously recognized location in a new maze, indicating they have spatial localization ability.

High-resolution small RNAs landscape provides insights into alkane adaptation in the marine alkane-degrader Alcanivorax dieselolei B-5

This study identifies sRNA candidates in Alcanivorax dieselolei B-5 under alkane and non-alkane conditions, revealing their roles in alkane metabolism and adaptation.

Diving Behavior Reveals Humidity Sensing Ability of Water Deprived Planarians

This study shows that aquatic planarians can sense humidity and use this ability to find water during drought by diving behavior.

Viruses Diversity and Interactions with Hosts in Deep-Sea Hydrothermal Vents

This study characterizes viral diversity and host interactions in deep-sea hydrothermal vents, revealing novel viral lineages and metabolic roles in host adaptation.

The frequent occurrence and metabolic versatility of Marinifilaceae bacteria involved in organic matter mineralizationas a key member in global deep sea

This paper identifies Marinifilaceae bacteria as key players in deep-sea organic matter mineralization, revealing their metabolic versatility and role in carbon and nitrogen cycling.

Potent Bacterial Vaccines Require FcγRIIB-mediated Pathogen Capture by Liver Sinusoidal Endothelium

This paper identifies FcγRIIB-mediated capture of antibody-coated bacteria by liver sinusoidal endothelial cells as a mechanism for superior vaccine efficacy.

Brassinosteroids signaling component SlBZR1 promotes fruit ripening in tomato

This study shows that brassinosteroids promote tomato fruit ripening by enhancing ethylene production and carotenoid accumulation through the SlBZR1 transcription factor.

Rapid Speciation Characterized by Incomplete Lineage Sorting in the Globally Distributed Bacterium Sulfitobacter

The paper identifies incomplete lineage sorting in Sulfitobacter, a marine bacterium, showing rapid speciation driven by ancestral polymorphism retention rather than adaptive selection.

Phosphorylation Status of B beta Subunit Acts as a Switch to Regulate the Function of Phosphatase PP2A in Ethylene-mediated Root Growth Inhibition

The paper shows that phosphorylation of Bβ subunit of PP2A acts as a switch to regulate PP2A activity, controlling EIR1 phosphorylation and auxin transport to modulate ethylene-mediated root growth inhibition.

Evolutionary ecology of microbial populations inhabiting deep sea sediments associated with cold seeps

The paper examines intraspecies diversity and evolutionary patterns of microbial populations in deep sea cold seep sediments, finding depth-dependent diversification and purifying selection on key metabolic genes.

Structure of IgG-Fc hexamer reveals a mutual lock-and-key mode of Fc-Fc interaction

The paper determines the structure of an IgG-Fc hexamer using cryo-EM, revealing a mutual lock-and-key interaction mode between Fc domains.

Kindlin-2 preserves integrity of the articular cartilage to protect against osteoarthritis

This study identifies Kindlin-2 as a protective factor in articular cartilage, showing its role in preventing osteoarthritis through regulation of Stat3 and Runx2 pathways.

Brassinosteroid signaling component SlBES1 promotes tomato fruit softening through transcriptional repression of PMEU1

This study identifies SlBES1 as a regulator of tomato fruit softening by repressing PMEU1, leading to firmer fruits with extended shelf life without affecting visual or nutritional quality.

DNA-PKcs phosphorylation at the T2609 cluster alters the repair pathway choice during immunoglobulin class switch recombination

This study shows that DNA-PKcs phosphorylation at T2609 cluster promotes cNHEJ repair pathway choice during CSR, as loss of this phosphorylation increases chromosomal translocation and alternative end-joining.

Abortion and various associated risk factors in dairy cow and sheep in Ili, China

This study investigates abortion rates and risk factors in dairy cows and sheep in Ili, China, identifying Brucella melitensis as the main pathogen and highlighting management factors contributing to reproductive issues.

Renewable Fatty Acid Ester Production in Clostridium

This paper develops microbial strains for producing renewable fatty acid esters, achieving high yields and economic competitiveness in bioproduction.