Author

J.-W. Huang

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Biochemistry· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Assay:proteomics· 2 Organism:bacteria (other)· 1 Approach:biophysical modeling· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1

Frequent Co-Authors

A. Acharya· 1 shared A. Ciccia· 1 shared C.-C. Chen· 1 shared E. Oldfield· 1 shared G. Han· 1 shared g. luan· 1 shared H. Bret· 1 shared H. Yang· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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1 shared paperBiochemistry

A. Acharya

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Mechanism of DNA unwinding by hexameric MCM8-9 in complex with HROB

A. Acharya, H. Bret, J.-W. Huang, M. Muetze, M. Goese, V. Kissling, R. Seidel, A. Ciccia, R. Guerois, P. Cejka

This study investigates how HROB regulates the DNA unwinding activity of the MCM8-9 helicase complex through structural and biochemical analyses.

bioRxiv · Jun 12, 2023 · PreprintBiochemistry

Phosphoantigens are Molecular Glues that Promote Butyrophilin 3A1/2A1 Association Leading to Vγ9Vδ2 T Cell Activation

L. Yuan, X. Ma, Y. Yang, X. Li, W. Ma, H. Yang, J.-W. Huang, J. Xue, S. Yi, M. Zhang, N. Cai, Q. Ding, L. Li, J. Duan, S. Malwal, , Y. Zhang

The paper shows phosphoantigens glue BTN3A1 and BTN2A1 together, initiating gamma-delta T cell activation through intracellular signaling.

bioRxiv · Jan 2, 2022 · PreprintImmunology

Wzc and WcaJ mutations in hypervirulent Klebsiella pneumoniae lead to phage resistance at the cost of reduced virulence

l. Song, X. Yang, J.-W. Huang, X. Zhu, G. Han, Y. Wan, Y. Xu, g. luan, X. Jia

This study identifies mutations in wzc and wcaJ genes in hypervirulent Klebsiella pneumoniae that confer phage resistance but reduce virulence.

bioRxiv · Apr 21, 2021 · PreprintMicrobiology

Degenerated virulence and irregular development of Fusarium oxysporum f. sp. niveum induced by successive subculture

T.-H. Chang, Y.-H. Lin, Y.-L. Wan, K.-S. Chen, J.-W. Huang, P.-F. L. Chang

This study shows that successive subculture of Fusarium oxysporum f. sp. niveum with aged mycelium leads to degeneration, reducing virulence through decreased cell wall-degrading enzyme activity and virulence gene expression.

bioRxiv · Oct 29, 2020Microbiology