Author

Jia Huang

Sir Run Run Shaw Hospital

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Same name, identified by ORCID

Biology Disciplines

Click to filter author papers

Cell Biology· 2 Molecular Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 3 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Bo-Xin Zhang· 2 shared Lei Wu· 2 shared Wei MoiD· 2 shared Zhang-Hua Yang· 2 shared Zhiyu CaiiD· 2 shared Baizhou LiiD· 1 shared Congrong Yang· 1 shared Haibing ZhangiD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersCell Biology

Bo-Xin Zhang

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

A direct RNA sequencing workflow for simultaneous profiling of tRNA abundance and modifications in mouse liver

Shenghong Dai, Zhaoyang Tian, Yaxuan Zhang, Xiaojing Li, Xinxin Yi, Ting Qiu, Liu Yang, Jin Ke, Min Chen, Jia Huang, Xinyu Hu, Yanqiang Li, Hu Chen, Tianyuan Zhang

This paper introduces a direct RNA sequencing workflow to profile tRNA abundance and modifications in mouse liver, identifying key modification sites and isotype-specific patterns.

bioRxiv · Oct 6, 2026 · PreprintMolecular Biology

Oxidation-Driven mtDNA B-Z Transition Activates ZBP1 to Mediate Acetaminophen Hepatotoxicity

Zhang-Hua Yang, Bo-Xin Zhang, Huan-Feng Ye, Liang Shi, Rui Gong, Zhiyu Cai, Qiang Chen, Lei Wu, Jia Huang, Le Zhang, Huipeng Jiao, Pinglong Xu, Qinjie Weng, Jie Zhang, Jinheng Pan, , Wei Mo

This study identifies oxidative mtDNA B-Z transitions activating ZBP1 as a key mechanism in APAP-induced liver failure and shows TH107854 can reverse this process.

Vita · Jan 1, 2026Peer-reviewedCell Biology

ZBP1 Senses Splicing Aberration through Z-RNA to promote Cell Death

Zhang-Hua Yang, Puqi Wu, Bo-Xin Zhang, Congrong Yang, Jia Huang, Lei Wu, Shaoyu Guo, Yuenan Zhou, Yuanhui Mao, Yafei Yin, Xiurong Wu, Pu Cheng, Baizhou Li, Rongbin Zhou, Han‐Ming Shen, , Wei Mo

This study shows that spliceosome inhibition generates Z-RNA, sensed by ZBP1 to trigger necroptosis in response to splicing aberrations.

Molecular Cell · Apr 22, 2025Peer-reviewedCell Biology