Author

Julian Mintseris

Harvard University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioinformatics· 1 Cell Biology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 1 Assay:protein sequence· 1 Assay:proteomics· 1 Approach:statistical model· 1 Research Focus:variant calling· 1

Frequent Co-Authors

Steven P. GygiiD· 3 shared Xin GuiD· 2 shared Amy S.Y. LeeiD· 1 shared Anna BesschetnovaiD· 1 shared Christopher NardoneiD· 1 shared Derrick Ekanayake· 1 shared Devin K. SchweppeiD· 1 shared Hsin-Yu Tsai· 1 shared

Activity by Year

2020-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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3 shared papersMolecular Biology

Steven P. GygiORCID

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Author profile →

3 papers

Recent·Most cited

Ribosome remodeling drives translation adaptation during viral infection and cellular stress

Hsin-Yu Tsai, Luochen Liu, Rebecca H. Fleming, Julian Mintseris, Derrick Ekanayake, Jing Guo, Xin Gu, Steven P. Gygi, Amy S.Y. Lee

The paper shows that ribosome remodeling enables enhanced viral protein synthesis during infection and cellular stress by altering ribosome composition and structure.

Molecular Cell · Oct 1, 2026Peer-reviewedMolecular Biology

Structural basis for the midnolin-proteasome pathway and its role in suppressing myeloma

Christopher Nardone, Jingjing Gao, Hyuk‐Soo Seo, Julian Mintseris, Lucy Ort, Matthew C. J. Yip, Milen Negasi, Anna Besschetnova, Nolan Kamitaki, Steven P. Gygi, Sirano Dhe‐Paganon, Nikhil C. Munshi, Mariateresa Fulciniti, Michael E. Greenberg, Sichen Shao, , Xin Gu

This study reveals the structural basis of the midnolin-proteasome pathway and shows that midnolin downregulation promotes myeloma cell survival by enhancing IRF4 expression.

Molecular Cell · Jun 17, 2025Peer-reviewedCell Biology

Improved Monoisotopic Mass Estimation for Deeper Proteome Coverage

Ramin Rad, Jiaming Li, Julian Mintseris, Jeremy D. O’Connell, Steven P. Gygi, Devin K. Schweppe

The paper introduces Monocle, an algorithm that improves monoisotopic mass estimation in proteomics, increasing peptide identifications by up to two-fold.

Journal of Proteome Research · Nov 16, 2020Peer-reviewedBioinformatics