Author

K. Doubrovinski

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 3 Cell Biology· 2

Signature Assays, Organisms & Methods

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Organism:Drosophila· 3 Approach:experimental assay· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Research Focus:development & morphogenesis· 2 Assay:imaging· 2 Approach:statistical model· 2 Research Focus:chromatin & epigenetic regulation· 1

Frequent Co-Authors

M. I. Cheikh· 2 shared M. Osterfield· 2 shared A. B. Hanker· 1 shared A. F. Carisey· 1 shared A. G. York· 1 shared A. L. Paek· 1 shared A. Marin· 1 shared A. Millett-Sikking· 1 shared

Activity by Year

2020-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 13 mutual co-author links

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2 shared papersBiophysics

M. I. Cheikh

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Author profile →

5 papers

Recent·Most cited

A scaling law for epithelial tissue rheology

M. I. Cheikh, N. Rodriguez, K. Doubrovinski

The paper develops a theory to explain the rheological properties of early fly embryos, showing that tissue deformation follows a power law with exponent 1/2 under pulling forces.

bioRxiv · Sep 12, 2023Biophysics

Tissue recoil in the early Drosophila embryo is a passive not active process

A. N. Goldner, S. M. Fessehaye, K. A. Mapes, M. Osterfield, K. Doubrovinski

The paper shows myosin activity is not required for tissue elasticity in Drosophila embryos and introduces methods for rapid protein inactivation and mechanical measurement.

bioRxiv · Aug 29, 2022 · PreprintCell Biology

A comprehensive model of Drosophila epithelium reveals the role of embryo geometry and cell topology in mechanical responses

M. I. Cheikh, J. Tchoufag, M. Osterfield, K. Dean, S. Bhaduri, C. Zhang, K. K. Mandadapu, K. Doubrovinski

The paper develops a model of Drosophila epithelium to show that mechanical responses depend on embryo geometry and cell topology, with apical surfaces being softer than basal ones.

bioRxiv · Aug 12, 2022Biophysics

Feedback in the β-catenin destruction complex imparts bistability and cellular memory

M. J. Cantoria, E. Alizadeh, J. Ravi, N. Bunnag, A. N. Kettenbach, Y. Ahmed, A. L. Paek, J. J. Tyson, K. Doubrovinski, E. Lee, C. A. Thorne

The paper shows that positive feedback in the β-catenin destruction complex creates bistability and memory in Wnt signaling, leading to switch-like cellular responses.

bioRxiv · Jan 28, 2022Cell Biology

A Versatile Oblique Plane Microscope for Large-Scale and High-Resolution Imaging of Subcellular Dynamics.

E. Sapoznik, B.-J. Chang, J. Huh, R. J. Ju, E. Azarova, T. Pohlkamp, E. S. Welf, D. Broadbent, A. F. Carisey, S. J. Stehbens, K.-m. Lee, A. Marin, A. B. Hanker, J. C. Schmidt, C. L. Arteaga, , R. P. Fiolka

This paper introduces an improved oblique plane microscope with enhanced resolution and usability, demonstrating its application in imaging various subcellular dynamics and challenging biological phenomena.

bioRxiv · Apr 7, 2020Biophysics