E. Sapoznik

Imaging of cellular dynamics in vitro and in situ: from a whole organism to sub-cellular imaging with self-driving, multi-scale microscopy

The paper introduces a self-driving, multi-resolution light-sheet microscope to simultaneously observe sub-cellular dynamics and whole organisms over extended periods, applying it to study development, cancer, and immune interactions in zebrafish.

Resolution doubling in light-sheet microscopy via oblique plane structured illumination

This paper demonstrates isotropic resolution doubling in light-sheet microscopy using oblique plane structured illumination, achieving sub-150nm lateral resolution with reduced phototoxicity and faster volumetric imaging.

Increasing the Field-of-View in Oblique Plane Microscopy via optical tiling

This paper introduces a dual-axis scan unit for oblique plane microscopy to increase field-of-view and imaging speed, enabling high-resolution volumetric imaging of zebrafish embryos.

Proteolysis-free cell migration through crowded environments via mechanical worrying

The paper shows amoeboid melanoma cells migrate through crowded environments by mechanically degrading extracellular matrix via bleb-driven abrading, without proteolysis.

Real-Time Multi-Angle Projection Imaging of Biological Dynamics

This paper introduces a projection imaging method that enables real-time, multi-angle visualization of biological processes with reduced data overhead.

A Versatile Oblique Plane Microscope for Large-Scale and High-Resolution Imaging of Subcellular Dynamics.

This paper introduces an improved oblique plane microscope with enhanced resolution and usability, demonstrating its application in imaging various subcellular dynamics and challenging biological phenomena.

Converting lateral scanning into axial focusing to speed up 3D microscopy

This paper introduces an optical design that converts lateral scanning into axial focusing, enabling rapid, high-resolution 3D imaging with axially swept light-sheet microscopy.