Author

A. F. Carisey

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Biophysics· 1 Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:cell signaling & trafficking· 3 Organism:human· 3 Assay:proteomics· 3 Research Focus:cell type annotation· 2 Research Focus:development & morphogenesis· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:chromatin & epigenetic regulation· 1

Frequent Co-Authors

C. I. Charendoff· 2 shared L. Bouchier-Hayes· 2 shared A. B. Hanker· 1 shared A. Boice· 1 shared A. G. York· 1 shared A. J. Faruqi· 1 shared A. Marin· 1 shared A. Millett-Sikking· 1 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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Curved chords = mutual co-authorship

2 shared papersCancer Biology

C. I. Charendoff

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Caspase-2 is essential for proliferation and self-renewal of nucleophosmin-mutated acute myeloid leukemia.

D. Sakthivel, A. N. Brown-Suedel, F. Keane, S. Huang, K. Mc Sherry, C. I. Charendoff, K. P. Dunne, D. J. Robichaux, B. Le, C. S. Shin, A. F. Carisey, J. M. Flanagan, L. Bouchier-Hayes

This study shows caspase-2 is essential for proliferation and self-renewal of NPM1-mutated AML cells, suggesting it as a potential therapeutic target.

bioRxiv · May 29, 2023Cancer Biology

Proteomic profiling of isolated immune synapses from primary mouse B cells

D. M. Cunha, S. Hernandez-Perez, L. O. Awoniyi, A. F. Carisey, G. Jacquemet, P. Mattila

This study isolates and profiles immune synapses from primary mouse B cells to identify proteins involved in early activation by surface-bound antigens, revealing novel components and pathways.

bioRxiv · Feb 23, 2023 · PreprintImmunology

Caspase-2 regulates S-phase cell cycle events to protect from DNA damage accumulation independent of apoptosis

A. Boice, R. K. Pandita, K. Lopez, M. J. Pourpak, C. I. Charendoff, V. K. Charaka, A. F. Carisey, T. K. Pandita, L. Bouchier-Hayes

This study shows caspase-2 regulates S-phase cell cycle events to reduce DNA damage accumulation without relying on its pro-apoptotic function.

bioRxiv · Mar 30, 2021Cell Biology

A Versatile Oblique Plane Microscope for Large-Scale and High-Resolution Imaging of Subcellular Dynamics.

E. Sapoznik, B.-J. Chang, J. Huh, R. J. Ju, E. Azarova, T. Pohlkamp, E. S. Welf, D. Broadbent, A. F. Carisey, S. J. Stehbens, K.-m. Lee, A. Marin, A. B. Hanker, J. C. Schmidt, C. L. Arteaga, , R. P. Fiolka

This paper introduces an improved oblique plane microscope with enhanced resolution and usability, demonstrating its application in imaging various subcellular dynamics and challenging biological phenomena.

bioRxiv · Apr 7, 2020Biophysics

Genetic immunodeficiency and autoimmune disease reveal distinct roles of Hem1 in the WAVE2 and mTORC2 complexes

W. A. Comrie, M. C. Poli, S. A. Cook, M. Similuk, A. Oler, A. J. Faruqi, D. B. Kuhns, S. Yang, A. F. Carisey, B. Fournier, D. E. Anderson, S. Price, W. A. Chahla, A. Vargas-Hernandez, L. R. Forbes, , M. J. Lenardo

Hem1 loss-of-function mutations cause congenital immunodysregulation by disrupting WAVE2 and mTORC2 complexes, leading to immunodeficiency and immune hyperresponsiveness.

bioRxiv · Jul 4, 2019 · PreprintImmunology