Author

K. Frueh

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 3 Organism:rat· 3 Assay:proteomics· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:clustering· 1 Research Focus:development & morphogenesis· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

A. Kaur· 2 shared C. Chan· 2 shared C. E. Otero· 2 shared D. Malouli· 2 shared D. N. Streblow· 2 shared E. A. Scheef· 2 shared H. Taher· 2 shared L. J. Picker· 2 shared

Activity by Year

2020-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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Curved chords = mutual co-authorship

2 shared papersMicrobiology

A. Kaur

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Rhesus Cytomegalovirus-encoded Fcγ-binding glycoproteins facilitate viral evasion from IgG-mediated humoral immunity

C. E. Otero, S. Petkova, M. Ebermann, H. Taher, N. John, K. Hoffmann, A. Davalos, M. J. Mostrom, R. M. Gilbride, C. Papen, A. Barber-Axthelm, E. A. Scheef, R. Barfield, L. M. Sprehe, S. Kendall, , P. Kolb

This study identifies and characterizes Rhesus CMV-encoded Fcγ-binding glycoproteins, showing they delay antibody-mediated immune control during primary infection.

Nature Communications · Jan 31, 2025Peer-reviewedMicrobiology

The pentameric complex is not required for vertical transmission of cytomegalovirus in seronegative pregnant rhesus macaques

H.-Y. Wang, H. Taher, C. N. Kreklywich, K. A. Schmidt, E. A. Scheef, R. Barfield, C. E. Otero, S. Valencia, C. M. Crooks, A. Mirza, K. Woods, N. V. Burgt, T. F. Kowalik, P. A. Barry, S. G. Hansen, , D. Malouli

The study shows that deleting the pentameric complex in rhesus CMV does not affect congenital transmission in seronegative pregnant rhesus macaques.

bioRxiv · Jun 15, 2023 · PreprintMicrobiology

HLA-E restricted, HIV-1 suppressing, Gag specific CD8+ T cells offer universal vaccine opportunities

H. Yang, M. Rei, S. Brackenridge, E. Brenna, H. Sun, s. abdulhaqq, M. K. Liu, W. Ma, P. Kurupati, x. Xu, V. Cerundolo, E. Jenkins, S. J. Davis, J. B. Sacha, K. Frueh, , A. J. McMichael

The paper demonstrates that HLA-E restricted, HIV-1 specific CD8+ T cells can suppress HIV-1 replication in vitro, suggesting potential for a universal vaccine.

bioRxiv · Dec 1, 2020 · PreprintImmunology