Author

J. W. Franses

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Bioengineering· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Research Focus:differential expression· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:gene regulatory network inference· 1 Research Focus:host-pathogen & immune response· 1 Assay:proteomics· 1

Frequent Co-Authors

D. T. Ting· 2 shared L. Nieman· 2 shared Y. Song· 2 shared A. Bardia· 1 shared A. Deshpande· 1 shared A. K. Coley· 1 shared A. M. Egloff· 1 shared A. Mishra· 1 shared

Activity by Year

2023-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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2 shared papersBioengineering

D. T. Ting

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Tumor cell-based liquid biopsy using high-throughput microfluidic enrichment of entire leukapheresis product

A. Mishra, S.-B. Huang, T. Dubash, R. Burr, B. S. Wittner, Q. E. Cunneely, V. R. Putaturo, A. Deshpande, E. Antmen, K. A. Gopinathan, K. Otani, Y. Miyazawa, J. E. Kwak, S. Y. Guay, J. Kelly, , M. Toner

This study uses high-throughput microfluidic technology to enrich CTCs from large blood volumes, enabling detailed molecular and morphological analysis of tumor cells in metastatic cancer patients.

bioRxiv · Mar 13, 2024 · PreprintBioengineering

Single Cell Spatial Transcriptomic Profiling Identifies a LINE1 Associated Disarrayed Immune Microenvironment in Hepatocellular Carcinoma

A. K. Coley, C. Nawrocki, B. K. Patel, A. Pankaj, Z. Guo, M. J. Emmett, E. R. Lang, Y. Song, K. H. Xu, C. R. Ferrone, V. Deshpande, L. T. Nieman, M. Aryee, J. W. Franses, D. T. Ting

This study uses single cell spatial transcriptomics to show LINE1 repeat RNA expression in HCC correlates with a disorganized immune microenvironment and poor patient survival.

bioRxiv · Dec 4, 2023 · PreprintCancer Biology

Ultrasensitive detection of circulating LINE-1 ORF1p as a specific multi-cancer biomarker

M. S. Taylor, W. Connie, P. C. Fridy, S. J. Zhang, Y. Senussi, J. C. Wolters, W.-C. Cheng, J. Heaps, B. D. Miller, K. Mori, L. Cohen, H. Jiang, K. R. Molloy, B. L. Norden, B. T. Chait, , O. H. Yilmaz

This study develops ultrasensitive assays to detect ORF1p in plasma, showing its potential as a multi-cancer biomarker for early detection and monitoring.

bioRxiv · Jan 25, 2023 · PreprintCancer Biology