Author

K. Kano

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Approach:genetic perturbation / CRISPR· 1 Organism:human· 1 Assay:metabolomics· 1

Frequent Co-Authors

J. Aoki· 2 shared A. Engler· 1 shared A. O'Connor· 1 shared C. Hinz· 1 shared D. Slatter· 1 shared D. White· 1 shared H. Komano· 1 shared H. Saito· 1 shared

Activity by Year

2019-2020 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersBiochemistry

J. Aoki

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Author profile →

2 papers

Recent·Most cited

Suppression of amyloid-β secretion from neurons by cis-9, trans-11-octadecadienoic acid, an isomer of conjugated linoleic acid

S. Hata, K. Kikuchi, K. Kano, H. Saito, Y. Sobu, S. Kinoshita, T. Saito, T. C. Saido, Y. Sano, H. Taru, J. Aoki, H. Komano, T. Tomita, S. Natori, T. Suzuki

This study shows that c9,t11 CLA reduces amyloid-beta production in neurons by altering BACE1 and APP localization, potentially protecting against neurodegeneration.

bioRxiv · Sep 13, 2020Biochemistry

Metabolic dysregulation of the lysophospholipid/autotaxin axis in the chromosome 9p21 gene SNP rs10757274

S. Meckelmann, J. Hawksworth, D. White, R. Andrews, P. Rodrigues, A. O'Connor, J. Alvarez Jarreta, V. Tyrrell, C. Hinz, Y. Zhou, J. Williams, M. Aldrovandi, W. J. Watkins, A. Engler, D. Slatter, , V. B. O'Donnell

The paper identifies metabolic dysregulation of lysophospholipid/autotaxin pathways linked to a CHD risk SNP, showing altered lipid metabolism and enzyme expression in multiple models.

bioRxiv · Oct 2, 2019Physiology