Author

K. Paeschke

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Immunology· 3

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1

Frequent Co-Authors

T. Zillinger· 2 shared A. Gerbaulet· 1 shared A. Gruenewald· 1 shared A. K. de Regt· 1 shared A. Kirchhoff· 1 shared A. Roers· 1 shared A.-K. Classen· 1 shared B. Putschli· 1 shared

Activity by Year

2022-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersImmunology

T. Zillinger

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

DNA damage signaling in Drosophila macrophages modulates systemic cytokine levels in response 1 to oxidative stress

F. Hersperger, T. Meyring, P. Weber, C. Chhatbar, G. Monaco, M. S. Dionne, K. Paeschke, M. Prinz, O. Gross, A.-K. Classen, K. Kierdorf

This study identifies DNA damage signaling in Drosophila macrophages as a key regulator of cytokine release and oxidative stress response through JNK and unpaired-3.

bioRxiv · Feb 22, 2023 · PreprintImmunology

A conserved isoleucine in the binding pocket of RIG-I controls immune tolerance to mitochondrial RNA

A. K. de Regt, K. Anand, K. Ciupka, K. Gatterdam, B. Putschli, D. Fusshoeller, D. Hilbig, A. Kirchhoff, C. Hunkler, S. Wolter, A. Gruenewald, C. Schuberth-Wagner, J. Ludwig, K. Paeschke, E. Bartok, , M. Schlee

This study identifies an isoleucine residue in RIG-I that prevents recognition of 5p-RNA, thereby maintaining immune tolerance to mitochondrial RNA.

bioRxiv · Aug 2, 2022Immunology

cGAS/STING-DEPENDENT SENSING OF ENDOGENOUS RNA

T. Schumann, S. C. Ramon, N. Schubert, M. A. Mayo, M. Hega, S.-R. Ada, L. Sydow, M. Hajikazemi, Y. Ge, M. Badstübner, S. Lienenklaus, B. Utess, L. Muhandes, M. Haase, L. Müller, , R. Behrendt

The paper shows that loss of SAMHD1 leads to chronic DNA damage and cGAS/STING-dependent type I interferon production in mice, linking it to autoimmunity and cancer.

bioRxiv · May 16, 2022Immunology