Author

J. Talbot

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3 Cell Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:mouse· 4 Research Focus:cell type annotation· 3 Assay:proteomics· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:host-pathogen & immune response· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1

Frequent Co-Authors

D. R. Littman· 3 shared A. L. Cook· 2 shared A. W. Hewitt· 2 shared L. Kroehling· 2 shared R. Kedmi· 2 shared A. Chen· 1 shared A. Grayson· 1 shared A. J. Fortune· 1 shared

Activity by Year

2019-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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3 shared papersImmunology

D. R. Littman

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Author profile →

5 papers

Recent·Most cited

Genetic and cellular basis of impaired phagocytosis and photoreceptor degeneration in CLN3 disease.

J. Han, S. Chear, J. Talbot, V. J. Swier, C. Booth, C. I. Reuben-Thomas, S. Dalvi, J. M. Weimer, A. W. Hewitt, A. L. Cook, R. Singh

This study investigates how CLN3 mutations impair phagocytosis and cause photoreceptor degeneration in CLN3 disease using patient-derived cells and a miniswine model.

bioRxiv · Jun 9, 2024Cell Biology

Induced pluripotent stem cell derived pericytes respond to endogenous mediators of proliferation and contractility

N. E. King, J.-M. Courtney, L. S. Brown, A. J. Fortune, N. B. Blackburn, J. L. Fletcher, J. M. Cashion, J. Talbot, A. Pebay, A. W. Hewitt, G. P. Morris, K. M. Young, A. L. Cook, B. A. Sutherland

This study compares iPSC-derived pericytes to primary human brain vascular pericytes, showing they express pericyte markers and respond to growth factors and vasoactive mediators, though with gene expression differences.

bioRxiv · Sep 29, 2023Cell Biology

Microbiota-instructed regulatory T cell differentiation is mediated by a distinct RORγt+ antigen presenting cell subset

R. Kedmi, T. Najar, K. R. Mesa, A. Grayson, L. Kroehling, Y. Hao, S. Hao, M. Pokrovskii, M. Xu, J. Talbot, J. Wang, J. Germino, C. A. Lareau, A. T. Satpathy, M. S. Anderson, , D. R. Littman

This study identifies a distinct RORγt+ antigen presenting cell subset that mediates microbiota-driven regulatory T cell differentiation, revealing a mechanism for maintaining immune tolerance.

bioRxiv · Nov 19, 2021 · PreprintImmunology

Redundant cytokine requirement for intestinal microbiota-induced Th17 cell differentiation in draining lymph nodes

T. Sano, T. Kageyama, V. Fang, R. Kedmi, J. Talbot, A. Chen, R. Kurakake, Y. Yang, C. Ng, S. R. Schwab, D. R. Littman

This study identifies redundant cytokine signals, particularly IL-6, IL-21, and IL-23, that drive Th17 cell differentiation in mesenteric lymph nodes induced by segmented filamentous bacteria.

bioRxiv · Apr 21, 2020Immunology

VIP-producing enteric neurons interact with innate lymphoid cells to regulate feeding-dependent intestinal epithelial barrier functions

J. Talbot, P. Hahn, L. Kroehling, H. Nguyen, D. Li, D. R. Littman

This study shows that VIP-producing enteric neurons interact with ILC3 to regulate intestinal barrier functions and nutrient absorption during feeding.

bioRxiv · Dec 7, 2019Immunology