Author

M. Pokrovskii

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 5

Signature Assays, Organisms & Methods

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Organism:mouse· 5 Research Focus:cell type annotation· 4 Approach:experimental assay· 4 Research Focus:cell signaling & trafficking· 2 Research Focus:gene regulatory network inference· 2 Research Focus:host-pathogen & immune response· 2 Assay:proteomics· 2 Assay:scRNA-seq· 2

Frequent Co-Authors

D. R. Littman· 5 shared J. A. Hall· 2 shared L. Kroehling· 2 shared M. Xu· 2 shared R. Bonneau· 2 shared R. Yi· 2 shared A. Grayson· 1 shared A. T. Satpathy· 1 shared

Activity by Year

2017-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 28 mutual co-author links

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5 shared papersImmunology

D. R. Littman

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Author profile →

5 papers

Recent·Most cited

Microbiota-instructed regulatory T cell differentiation is mediated by a distinct RORγt+ antigen presenting cell subset

R. Kedmi, T. Najar, K. R. Mesa, A. Grayson, L. Kroehling, Y. Hao, S. Hao, M. Pokrovskii, M. Xu, J. Talbot, J. Wang, J. Germino, C. A. Lareau, A. T. Satpathy, M. S. Anderson, , D. R. Littman

This study identifies a distinct RORγt+ antigen presenting cell subset that mediates microbiota-driven regulatory T cell differentiation, revealing a mechanism for maintaining immune tolerance.

bioRxiv · Nov 19, 2021 · PreprintImmunology

RORα enforces stability of the T-helper-17 cell effector program

J.-Y. Lee, J. A. Hall, M. Pokrovskii, L. Kroehling, L. Wu, D. R. Littman

This study shows ROR is essential for maintaining Th17 cell effector function through cooperative binding with ROR{gamma}t to an enhancer element.

bioRxiv · Dec 15, 2020 · PreprintImmunology

Deciphering the Regulatory Landscape of γδ T Cell Development by Single-Cell RNA-Sequencing

Sagar, M. Pokrovskii, J. S. Herman, S. Naik, E. Sock, U. Lausch, M. Wegner, Y. Tanriver, D. R. Littman, D. Grün

This study uses single-cell RNA-sequencing to uncover the developmental trajectory of γδ T cells, identifying c-MAF as a key regulator of IL-17-producing γδ T cell differentiation.

bioRxiv · Nov 27, 2018 · PreprintImmunology

Transcriptional regulatory networks that promote and restrict identities and functions of intestinal innate lymphoid cells

M. Pokrovskii, J. A. Hall, D. E. Ochayon, R. Yi, N. S. Chaimowitz, H. Seelamneni, N. Carriero, A. Watters, S. N. Waggoner, D. R. Littman, R. Bonneau, E. R. Miraldi

This study identifies transcriptional regulatory networks in intestinal ILC subsets, revealing key transcription factors and their roles in lineage identity and plasticity.

bioRxiv · Nov 8, 2018Immunology

c-Maf-dependent regulatory T cells mediate immunological tolerance to intestinal microbiota

M. Xu, M. Pokrovskii, Y. Ding, R. Yi, C. Au, C. Galan, R. Bonneau, D. R. Littman

This study identifies c-Maf-dependent regulatory T cells that suppress inflammation caused by the pathobiont Helicobacter hepaticus, preventing colitis in mice.

bioRxiv · Apr 22, 2017Immunology