Star-Shaped Glatiramer Acetate Mitigates Pulmonary Dysfunction and Brain Neurodegeneration in a Murine Model of Cryptococcus-Associated IRIS
Shehata Anwar, Jinyan Zhou, Lauren Kowalski, Joshua Saylor, Devanshi Shukla, Katelyn Boetel, Ziyuan Song, Kamal Sharma, Jianjun Cheng, Makoto Inoue
This study tests star-shaped glatiramer acetate in a murine C-IRIS model, finding it reduces Th1 cells and neurodegeneration while improving lung function and survival.
bioRxiv · Jan 7, 2025 · PreprintImmunology