Author

Kee-Ming Chia

Garvan Institute of Medical Research

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Molecular Biology· 2

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:differential expression· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Organism:mouse· 2 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Catherine Elizabeth CaldoniD· 2 shared Clare StirzakeriD· 2 shared Elgene LimiD· 2 shared Elyssa M. CampbelliD· 2 shared Joanna Achinger-KaweckaiD· 2 shared Neil PortmaniD· 2 shared Qian DuiD· 2 shared Shalima S. Nair· 2 shared

Activity by Year

2021-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersMolecular Biology

Catherine Elizabeth CaldonORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Epigenetic therapy targets the 3D epigenome in endocrine-resistant breast cancer

Joanna Achinger-Kawecka, Clare Stirzaker, Neil Portman, Elyssa M. Campbell, Kee-Ming Chia, Qian Du, Geraldine Laven‐Law, Shalima S. Nair, Aliza Yong, Ashleigh Wilkinson, Samuel Clifton, Heloisa Helena Milioli, Sarah Alexandrou, Catherine Elizabeth Caldon, Jenny Z. Song, , Susan J. Clark

This study shows that Decitabine suppresses tumour growth in ER+ breast cancer by inducing DNA hypomethylation and altering 3D chromatin structure.

Nature Structural & Molecular Biology · Jan 5, 2024Peer-reviewedMolecular Biology

DNA methylation is required to maintain DNA replication timing precision and 3D genome integrity

Qian Du, Grady C. Smith, Phuc‐Loi Luu, James M. Ferguson, Nicola J. Armstrong, Catherine Elizabeth Caldon, Elyssa M. Campbell, Shalima S. Nair, Elena Zotenko, Cathryn M. Gould, Michael J Buckley, Kee-Ming Chia, Neil Portman, Elgene Lim, Dominik C. Kaczorowski, , Susan J. Clark

This study shows DNA hypomethylation disrupts replication timing precision and 3D genome organisation in colorectal cancer DNMT1 and DNMT3B knockout cells.

Cell Reports · Sep 1, 2021Peer-reviewedMolecular Biology