Author
Garvan Institute of Medical Research
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
4 papers
Recent·Most cited
Joanna Achinger-Kawecka, Clare Stirzaker, Neil Portman…·Susan J. Clark
This study shows that Decitabine suppresses tumour growth in ER+ breast cancer by inducing DNA hypomethylation and altering 3D chromatin structure.
Qian Du, Grady C. Smith, Phuc‐Loi Luu…·Susan J. Clark
This study shows DNA hypomethylation disrupts replication timing precision and 3D genome organisation in colorectal cancer DNMT1 and DNMT3B knockout cells.
Ulf Schmitz, Jaynish S. Shah, Bijay P. Dhungel…·John E.J. Rasko
The paper shows that chronic myeloid leukemia patients in molecular remission still have widespread aberrant alternative splicing, unlike normal gene expression and DNA methylation patterns.
Qian Du, Saul A. Bert, Nicola J. Armstrong…·Susan J. Clark
This study shows that replication timing influences epigenetic changes and chromosomal rearrangements in cancer by linking early and late replication to specific methylation and histone modifications.