Author

Kieran P. Higgins

Netherlands Institute for Neuroscience

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Research Focus:cell type annotation· 1 Organism:human· 1 Assay:spatial transcriptomics· 1

Frequent Co-Authors

Maarten H. P. KoleiD· 3 shared Bastiaan Lodder· 2 shared Alex X.Y. Klinkenberg· 1 shared Andrew J. DworkiD· 1 shared Anna M. SteyeriD· 1 shared Boguslawa SadowskiiD· 1 shared Carolina ManganaiD· 1 shared Daan van der VlietiD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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3 shared papersNeuroscience

Maarten H. P. KoleORCID

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Author profile →

3 papers

Recent·Most cited

An organotypic neocortical slice culture for studying neuroglial interactions

Kieran P. Higgins, Viktor A.B. Al Naqib, Pierre Mayo, Bastiaan Lodder, Takahiro Masuda, Lukas Amann, Marco Prinz, Maarten H. P. Kole

This study develops an organotypic neocortical slice culture to study neuroglial interactions across development and disease states.

bioRxiv · May 15, 2026 · PreprintNeuroscience

Tether-mediated extraction of myelinoid bodies by microglia and astrocytes can maintain myelin integrity

Erik Späte, Kieran P. Higgins, Yeonsu Kim, Carolina Mangana, Lina Komarek, Mohammadhossein Teymouri, Ulrike C. Gerwig, Svea Melzer, Boguslawa Sadowski, Torben Ruhwedel, Predrag Janjić, Bastiaan Lodder, Andrew J. Dwork, Maarten H. P. Kole, Anna M. Steyer, , Sandra Goebbels

The paper shows that microglia and astrocytes extract myelinoid bodies via tethers, preserving myelin sheath integrity through tension-driven scission and fusion.

bioRxiv · Dec 9, 2025 · PreprintNeuroscience

Spatially resolved mapping of monoacylglycerol lipase activity in the brain

Daan van der Vliet, Alex X.Y. Klinkenberg, Rik Platte, Kieran P. Higgins, Susanne Prokop, Mirjam C. W. Huizenga, Lars Kraaijevanger, Noëlle van Egmond, Verena M. Straub, Maarten H. P. Kole, Pál Pacher, István Katona, Inge Huitinga, Mario van der Stelt

The paper introduces fluorescent activity-based probes to map MAGL activity in brain tissues, revealing its spatial distribution in mouse and human brains.

ACS Chemical Neuroscience · Nov 28, 2025Peer-reviewedNeuroscience