Author

Ulrike C. Gerwig

Max Planck Institute for Multidisciplinary Sciences

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Neuroscience· 3

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Approach:experimental assay· 3 Organism:mouse· 3 Assay:electronic health records· 1

Frequent Co-Authors

Klaus‐Armin NaveiD· 3 shared Sandra GoebbelsiD· 3 shared Wiebke MöbiusiD· 3 shared Julia M. EdgariD· 2 shared Lina KomarekiD· 2 shared Yeonsu KimiD· 2 shared Alexandra I. MotiD· 1 shared Andrew J. DworkiD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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3 shared papersNeuroscience

Klaus‐Armin NaveORCID

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3 papers

Recent·Most cited

A myelinic channel system for motor-driven organelle transport

Katie J. Chapple, Tabitha R. F. Green, Kristen H. Schuster, Sarah Wirth, Yi-Hsin Chen, Ulrike C. Gerwig, Marie Louise Aicher, Yeonsu Kim, Lina Komarek, Angus M. Brown, Colin L. Crawford, Rebecca Sherrard Smith, Young Seok Lee, Lauren Elaine Black, Luis Pardo, , Julia M. Edgar

The paper identifies the myelinic channel system as a pathway for microtubule-dependent organelle transport in oligodendrocytes, showing its role in maintaining axonal integrity through neuronal activity and motor proteins.

Nature Neuroscience · Jul 31, 2026Peer-reviewedNeuroscience

Mutant SOD1 expressed by oligodendrocytes aggregates in myelinic nanochannels and accelerates disease progression in familial ALS mice

Alexandra I. Mot, Ying Li, Payam Dibaj, Iva D. Tzvetanova, Ulrike C. Gerwig, Tizibt Ashine Bogale, Sandra Goebbels, Wiebke Möbius, Dwight E. Bergles, Brett M. Morrison, Jeffrey D. Rothstein, Don W. Cleveland, Julia M. Edgar, Klaus‐Armin Nave

This study shows that mutant SOD1 aggregates in myelinic nanochannels and accelerates ALS progression in mice, highlighting the role of myelin channel integrity in disease.

bioRxiv · Jun 11, 2026 · PreprintNeuroscience

Tether-mediated extraction of myelinoid bodies by microglia and astrocytes can maintain myelin integrity

Erik Späte, Kieran P. Higgins, Yeonsu Kim, Carolina Mangana, Lina Komarek, Mohammadhossein Teymouri, Ulrike C. Gerwig, Svea Melzer, Boguslawa Sadowski, Torben Ruhwedel, Predrag Janjić, Bastiaan Lodder, Andrew J. Dwork, Maarten H. P. Kole, Anna M. Steyer, , Sandra Goebbels

The paper shows that microglia and astrocytes extract myelinoid bodies via tethers, preserving myelin sheath integrity through tension-driven scission and fusion.

bioRxiv · Dec 9, 2025 · PreprintNeuroscience