Stefan Ebner

The paper shows NLRP3 activators disrupt the AP2 complex and impair plasma membrane signaling, leading to inflammation and cell death.

This study shows that multiple clustered centrosomes in antigen-presenting cells enhance T cell activation by positioning near the cell center, unlike T cells where centrosomes polarize toward the immune synapse.

The paper introduces a method to identify covalent modifications and protein interactions regulating immune signaling complex composition and function in monocytes.

This study investigates how CD81 senses cholesterol and how this affects its function as a hepatitis C virus receptor, finding that cholesterol binding regulates CD81's conformation and receptor activity.