Author

L. Huo

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Microbiology· 2 Cancer Biology· 1 Plant Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:host-pathogen & immune response· 3 Assay:bulk RNA-seq· 2 Research Focus:development & morphogenesis· 2 Assay:metagenomics· 2 Organism:mouse· 2 Approach:statistical model· 2 Organism:Arabidopsis· 1

Frequent Co-Authors

C. Wilson· 2 shared E. Bailey· 2 shared H. De Clippeleir· 2 shared I. Cotto· 2 shared K. Gilmore· 2 shared K. J. Vilardi· 2 shared W. Khunjar· 2 shared A. Dortfleutner· 1 shared

Activity by Year

2018-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersMicrobiology

C. Wilson

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Loss of TRIM21 drives UVB-induced systemic inflammation by regulating DNA-sensing pathways

G. Tumurkhuu, R. Moore, G. Perri, L. Huo, A. Naveen Kumar, G. De Los Santos, D. Gibb, J. Carriere, Y. M. Yu, R. Abuav, D. Wallace, M. Ishimori, W. Shon, A. Dortfleutner, C. Stehlik, C. Jefferies

This study shows that loss of TRIM21 increases UVB-induced systemic inflammation by enhancing IFN expression through impaired STING signaling in mice.

Arthritis & Rheumatology · Sep 10, 2025Peer-reviewedImmunology

Ultraviolet attenuates centromere-mediated meiotic genome stability and alters gametophytic ploidy consistency in flowering plants

H. Fu, J. Zhong, J. Zhao, L. Huo, C. Wang, D. Ma, W. Pan, L. Sun, Z.-M. Ren, T. Fan, Z. Wang, W. Wang, X. Lei, G. Yu, J. Li, , B. Liu

This study shows UV radiation reduces crossover rates and disrupts meiotic spindle organization in Arabidopsis, leading to unreduced gametes and altered genome stability.

bioRxiv · Feb 12, 2024Plant Biology

Low diversity and microdiversity of comammox bacteria in wastewater systems suggests wastewater-specific adaptation within the Ca. Nitrospira nitrosa cluster.

I. Cotto, K. J. Vilardi, L. Huo, E. C. Fogarty, W. Khunjar, C. Wilson, H. De Clippeleir, K. Gilmore, E. Bailey, S. J. Lücker, A. J. Pinto

The paper compares diversity and microdiversity of comammox bacteria with strict nitrifiers in wastewater systems, finding low diversity and specific adaptations in comammox populations.

bioRxiv · Jun 11, 2022Microbiology

NDRG1 expression is an independent prognostic factor in inflammatory breast cancer

E. Schlee Villodre, Y. Gong, L. Huo, E. C. Yoon, N. T. Ueno, W. A. Woodward, D. Tripathy, J. Song, B. G. Debeb

This study shows NDRG1 expression is an independent predictor of poor survival in inflammatory breast cancer patients.

bioRxiv · Sep 25, 2020Cancer Biology

Long solids retention times and attached growth phase favor prevalence of comammox bacteria in nitrogen removal systems.

I. Cotto, Z. Dai, L. Huo, C. L. Anderson, K. J. Vilardi, U. Z. Ijaz, W. Khunjar, C. Wilson, H. De Clippeleir, K. Gilmore, E. Bailey, A. Pinto

This study identifies conditions favoring comammox bacteria in wastewater treatment systems and develops a qPCR assay to quantify them.

bioRxiv · Jul 29, 2019Microbiology

Dominant negative FADD/MORT1 inhibits the development of intestinal intraepithelial lymphocytes with a marked defect on CD8αα+TCRγδ+ T cells

X. Zhang, L. Huo, L. Song, Z. Hu, X. Wang, Y. Han, Y. Wang, P. Xu, J. Zhang, Z.-C. Hua

This study shows that FADD is critical for intestinal intraepithelial lymphocyte (IEL) development, particularly affecting CD8αα+ TCRγδ+ T cells, and its loss worsens colitis.

bioRxiv · May 3, 2018Immunology