Author

L. K. Castro

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:proteomics· 2 Organism:C. elegans· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1 Assay:DNA methylation· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

A. G. Sanderlin· 1 shared A. P. Ryan· 1 shared B. V. Tsu· 1 shared C. M. Beierschmitt· 1 shared E. A. Turcotte· 1 shared E. J. Fay· 1 shared J. Kulsuptrakul· 1 shared J. L. Hyde· 1 shared

Activity by Year

2021-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperMicrobiology

A. G. Sanderlin

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Host specific sensing of coronaviruses and picornaviruses by the CARD8 inflammasome

B. V. Tsu, R. Agarwal, N. S. Gokhale, J. Kulsuptrakul, A. P. Ryan, L. K. Castro, C. M. Beierschmitt, E. A. Turcotte, E. J. Fay, R. E. Vance, J. L. Hyde, R. Savan, P. S. Mitchell, M. D. Daugherty

This study identifies CARD8 as a sensor for viral proteases, showing it activates inflammasomes in response to coronavirus 3CLpro and can be modulated by genetic variation.

bioRxiv · Sep 21, 2022Immunology

Activation of a signaling pathway by the physical translocation of a chromosome

M. Guzzo, A. G. Sanderlin, L. K. Castro, M. T. Laub

This study shows how DNA replication initiation in Caulobacter crescentus triggers the CtrA signaling pathway via chromosome translocation and ParA-mediated recruitment of ChpT.

bioRxiv · Mar 8, 2021Microbiology